SynthesisObstetrics and gynecology2009
Active compared with expectant delivery management in women with gestational diabetes: a systematic review.
Synthesis in Obstetrics and gynecology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07587632 (Natural Cervical Ripening to Prevent Pharmacological Induction of Labor - a Pilot Study.), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Natural Cervical Ripening to Prevent Pharmacological Induction of Labor - a Pilot Study.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Comparison of adverse maternal and perinatal outcomes between induction and expectant management among women with gestational diabetes mellitus at term pregnancy: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- Planned birth at or near term for improving health outcomes for pregnant women with gestational diabetes and their infants.The Cochrane database of systematic reviews · 2018Pooled it
- Randomized controlled trial of induction at 38 weeks versus 40 weeks gestation on maternal and infant outcomes in women with insulin-controlled gestational diabetes.Wiener klinische Wochenschrift · 2017Trial
- Diabetes mellitus: an independent predictor of duration of prostaglandin labor induction.Journal of perinatology : official journal of the California Perinatal Association · 2017Trial
- "GINEXMAL RCT: Induction of labour versus expectant management in gestational diabetes pregnancies".BMC pregnancy and childbirth · 2011Trial
- Outcomes after 39 weeks among pregnant patients with diet-controlled gestational diabetes mellitus.Pregnancy (Hoboken, N.J.) · 2026Article
- Gestational diabetes mellitus: The optimal time of delivery.World journal of diabetes · 2023Review
- Management of shoulder dystocia.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022Article
- Timing of delivery in women with diabetes: A population-based study.Acta obstetricia et gynecologica Scandinavica · 2020Article
- Gestational Age of Delivery in Pregnancies Complicated by Diabetes.Ochsner journal · 2020Article
- Updates in Gestational Diabetes Prevalence, Treatment, and Health Policy.Current diabetes reports · 2019Review
- Gestational diabetes from A to Z.World journal of diabetes · 2017Review
- Human Placental Hofbauer Cells Maintain an Anti-inflammatory M2 Phenotype despite the Presence of Gestational Diabetes Mellitus.Frontiers in immunology · 2017Article
- Maternal nutrition: opportunities in the prevention of gestational diabetes.Nutrition reviews · 2017Review
- Combined Metabolomic Analysis of Plasma and Urine Reveals AHBA, Tryptophan and Serotonin Metabolism as Potential Risk Factors in Gestational Diabetes Mellitus (GDM).Frontiers in molecular biosciences · 2017Article
- Labor and neonatal outcomes after term induction of labor in gestational diabetes.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
- What is the optimal gestational age for women with gestational diabetes type A1 to deliver?American journal of obstetrics and gynecology · 2014Article
- Diabetes in pregnancy: timing and mode of delivery.Current diabetes reports · 2014Review
- Timing of delivery in women with diabetes in pregnancy.Obstetric medicine · 2014Review
- High priority research needs for gestational diabetes mellitus.Journal of women's health (2002) · 2012Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe conducted a systematic review to estimate benefits and harms of the choice of timing of induction or elective cesarean delivery based on estimated fetal weight or gestational age in women with gestational diabetes mellitus (GDM). DATA SOURCES: An electronic literature search was performed using MEDLINE, EMBASE, the Cumulative Index to Nursing and Allied Health Literature, and The Cochrane Central Register of Controlled Trials from inception to January 2007. METHODS OF STUDY SELECTION: Two investigators independently reviewed titles and abstracts, assessed article quality, and abstracted data. Maternal outcomes included cesarean delivery and operative vaginal delivery. Neonatal outcomes included birth weight, macrosomia, large for gestational age, shoulder dystocia, birth trauma, neonatal intensive care admissions, and perinatal mortality. TABULATION, INTEGRATION, AND
resultsFive studies met our inclusion criteria: one randomized controlled trial (RCT) and four observational studies. The RCT (n=200) compared the effect of labor induction at term with expectant management. The proportion of newborns with birth weight greater than the 90th percentile was significantly greater in the expectant-management group (23% compared with 10% with active induction, P=.02); there were no significant differences in rates of cesarean delivery, shoulder dystocia, neonatal hypoglycemia, or perinatal deaths. The four observational studies suggest a potential reduction in macrosomia and shoulder dystocia with labor induction and cesarean delivery for estimated fetal weight indications, but there was insufficient evidence to assess other clinical outcomes.
conclusionActive rather than expectant management of labor at term for women with GDM may reduce rates of macrosomia and related complications. Further RCTs and observational studies with a broader range of outcomes are needed for sufficient evidence to inform clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.