ArticleProceedings of the National Academy of Sciences of the United States of America2008
Transgenic rice plants that overexpress transcription factors RF2a and RF2b are tolerant to rice tungro virus replication and disease.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 75 citations in OpenAlex.
- Natural variation of GNP2 enhances grain number to benefit rice yield.Nature communications · 2025Article
- Article
- OsRF2b interacting with OsbZIP61 modulates nitrogen use efficiency and grain yield via heterodimers in rice.Plant biotechnology journal · 2025Article
- Biotechnological breakthroughs in rice disease management: an overview from transgenics to CRISPR.Molecular biology reports · 2025Review
- Microbiome homeostasis on rice leaves is regulated by a precursor molecule of lignin biosynthesis.Nature communications · 2024Article
- Methane-derived microbial biostimulant reduces greenhouse gas emissions and improves rice yield.Frontiers in plant science · 2024Article
- Tailoring plant-associated microbial inoculants in agriculture: a roadmap for successful application.Journal of experimental botany · 2020Review
- OsbZIP81, A Homologue of Arabidopsis VIP1, May Positively Regulate JA Levels by Directly Targetting the Genes in JA Signaling and Metabolism Pathway in Rice.International journal of molecular sciences · 2019Article
- Proteomic and Phosphoproteomic Analysis in Tobacco Mosaic Virus-Infected Tobacco (Nicotiana tabacum).Biomolecules · 2019Article
- Calcium signalling regulates the functions of the bZIP protein VIP1 in touch responses in Arabidopsis thaliana.Annals of botany · 2018Article
- Utilization of engineered resistance to viruses in crops of the developing world, with emphasis on sub-Saharan Africa.Current opinion in virology · 2017Review
- Article
- VIP1 is very important/interesting protein 1 regulating touch responses of Arabidopsis.Plant signaling & behavior · 2016Article
- The bZIP Protein VIP1 Is Involved in Touch Responses in Arabidopsis Roots.Plant physiology · 2016Article
- A comprehensive quantitative phosphoproteome analysis of rice in response to bacterial blight.BMC plant biology · 2015Article
- Article
- Bacilliform DNA-containing plant viruses in the tropics: commonalities within a genetically diverse group.Molecular plant pathology · 2013Review
- Delay in virus accumulation and low virus transmission from transgenic rice plants expressing Rice tungro spherical virus RNA.Virus genes · 2012Article
- Detection of probable marker-free transgene-positive rice plants resistant to rice tungro disease from backcross progenies of transgenic Pusa Basmati 1.Journal of genetics · 2012Article
- Constitutive activation of transcription factor OsbZIP46 improves drought tolerance in rice.Plant physiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rice tungro disease (RTD) is a significant yield constraint in rice-growing areas of South and Southeast Asia. Disease symptoms are caused largely by infection by the rice tungro bacilliform virus (RTBV). Two host transcription factors, RF2a and RF2b, regulate expression of the RTBV promoter and are important for plant development. Expression of a dominant negative mutant of these factors in transgenic rice resulted in phenotypes that mimic the symptoms of RTD, whereas overexpression of RF2a and RF2b had essentially no impact on plant development. Conversely, lines with elevated expression of RF2a or RF2b showed weak or no symptoms of infection after Agrobacterium inoculation of RTBV, whereas control plants showed severe stunting and leaf discoloration. Furthermore, transgenic plants exhibited reduced accumulation of RTBV RNA and viral DNA compared with nontransgenic plants. Similar results were obtained in studies after virus inoculation by green leafhoppers. Gaining disease resistance by elevating the expression of host regulators provides another strategy against RTD and may have implications for other pararetrovirus infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.