ArticleImmunity2008
Alternative splicing of CD45: the tip of the iceberg.
Article in Immunity, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 41 citations in OpenAlex.
- Loss of ST8Sia6 mediated α-2,8-linked di-sialylation enhances T cell-dependent antibody responses and promotes autoimmunity in aged mice.Frontiers in immunology · 2026Article
- Get Spliced: Uniting Alternative Splicing and Arthritis.International journal of molecular sciences · 2024Review
- Re-evaluating the impact of alternative RNA splicing on proteomic diversity.Frontiers in genetics · 2023Review
- Single-cell atlas of peripheral blood mononuclear cells from pregnant women.Clinical and translational medicine · 2022Article
- The aberrant expression of CD45 isoforms and levels of sex hormones in systemic lupus erythematosus.Clinical rheumatology · 2022Article
- Article
- Review
- Estradiol regulates the expression of CD45 splicing isoforms in lymphocytes.Molecular biology reports · 2020Article
- Profiling the Atlantic Salmon IgMFrontiers in immunology · 2019Article
- Exploring the RNA Gap for Improving Diagnostic Yield in Primary Immunodeficiencies.Frontiers in genetics · 2019Review
- Monozygotic Twins Concordant for Common Variable Immunodeficiency: Strikingly Similar Clinical and Immune Profile Associated With a Polygenic Burden.Frontiers in immunology · 2019Article
- When one becomes many-Alternative splicing in β-cell function and failure.Diabetes, obesity & metabolism · 2018Review
- SpliceRCA:ACS central science · 2018Article
- Phenotypic characterization and anticancer capacity of CD8+ cytokine-induced killer cells after antigen-induced expansion.PloS one · 2017Article
- A Chemoattractant-Guided Walk Through Lymphopoiesis: From Hematopoietic Stem Cells to Mature B Lymphocytes.Advances in immunology · 2017Review
- The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.Cell reports · 2016Article
- The Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular Differentiation.International journal of molecular sciences · 2015Review
- Overexpression of CD45RA isoforms in carriers of the C77G mutation leads to hyporeactivity of CD4+CD25highFoxp3+ regulatory T cells.Genes and immunity · 2015Article
- Article
- An atlas of mouse CD4(+) T cell transcriptomes.Biology direct · 2015Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Mechanisms underlying the regulated splicing of CD45 RNA have been long-standing puzzles. In this issue of Immunity, Wu et al. (2008) identify hnRNPLL as a critical regulator of both signal-induced exon skipping in CD45 and global alternative-transcript expression in memory T cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.