Evidence map›Paper›PMID 19099583›Full record

SynthesisBMC surgery2008

Dacron vs. PTFE as bypass materials in peripheral vascular surgery--systematic review and meta-analysis.

Stephanie Roll, Jacqueline Müller-Nordhorn, Thomas Keil, Hans Scholz, Daniela Eidt, Wolfgang Greiner, Stefan N Willich

Abstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Graft type for femoro-popliteal bypass surgery.The Cochrane database of systematic reviews · 2018
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Salvaging unexpected vascular challenges in renal transplant: two case reports.International journal of surgery case reports · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Extracellular Matrix-Based Biomaterials for Cardiovascular Tissue Engineering.Journal of cardiovascular development and disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie RollInstitute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany. stephanie.roll@charite.de
Jacqueline Müller-Nordhorn
Thomas Keil
Hans Scholz
Daniela Eidt
Wolfgang Greiner
Stefan N Willich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn peripheral vascular bypass surgery different synthetic materials are available for bypass grafting. It is unclear which of the two commonly used materials, polytetrafluoroethylene (PTFE) or polyester (Dacron(R)) grafts, is to be preferred. Thus, the aim of this meta-analysis and systematic review was to compare the effectiveness of these two prosthetic bypass materials (Dacron and PTFE).

methodsWe performed a systematic literature search in MEDLINE, Cochrane-Library - CENTRAL, EMBASE and other databases for relevant publications in English and German published between 1999 and 2008. Only randomized controlled trials were considered for inclusion. We assessed the methodological quality by means of standardized checklists. Primary patency was used as the main endpoint. Random-effect meta-analysis as well as pooling data in life table format was performed to combine study results.

resultsNine randomized controlled trials (RCT) were included. Two trials showed statistically significant differences in primary patency, one favouring Dacron and one favouring PTFE grafts, while 7 trials did not show statistically significant differences between the two materials. Meta-analysis on the comparison of PTFE vs. Dacron grafts yielded no differences with regard to primary patency rates (hazard ratio 1.04 (95% confidence interval [0.85;1.28]), no significant heterogeneity (p = 0.32, I2 = 14%)). Similarly, there were no significant differences with regard to secondary patency rates.

conclusionSystematic evaluation and meta-analysis of randomized controlled trials comparing Dacron and PTFE as bypass materials for peripheral vascular surgery showed no evidence of an advantage of one synthetic material over the other.

Indexed as

Biocompatible MaterialsBlood Vessel ProsthesisPolyethylene TerephthalatesPolytetrafluoroethyleneHumansPeripheral Vascular DiseasesRandomized Controlled Trials as TopicVascular PatencyBiocompatible MaterialsPolyethylene TerephthalatesPolytetrafluoroethylene

Identifiers

PMID19099583
PMCPMC2645354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.