Evidence map›Paper›PMID 19099298›Full record

ArticlePediatric radiology2009

Brain ultrasonography findings in neonates with exposure to cocaine during pregnancy.

Marian van Huis, Anne A M W van Kempen, Myrthe Peelen, Maaike Timmers, Kees Boer, Bert J Smit, Rick R Van Rijn

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Ultrasound evaluation of brain parenchyma in preterm infants with prenatal opioid exposure.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marian van HuisDepartment of Obstetrics and Gynaecology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.
Anne A M W van Kempen
Myrthe Peelen
Maaike Timmers
Kees Boer
Bert J Smit
Rick R Van Rijn
Academic Medical Center · NLErasmus University Rotterdam · NLOLVG · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCocaine exposure during pregnancy has been reported to have detrimental effects on the fetus.

objectiveTo describe the findings on cranial ultrasonography (CUS) as part of a neonatal screening programme for exposed neonates. MATERIALS AND

methodsThe study was a semiprospective analysis of a 12-year cohort of neonates born to mothers who had used cocaine during their pregnancy and who had follow-up according to a strict clinical protocol.

resultsIn total, 154 neonates (78 boys, 76 girls) were included, of whom 29 (19%) were born preterm, and 125 (81%) were born full-term. Abnormalities on CUS were seen in 37 neonates (24%; 95% CI 18-31%). The abnormalities were classified as minor in 20 (13%; 95% CI 9-19%) and mildly abnormal in 17 (11%; 95% CI 7-17%). None of the infants showed severe abnormalities. The abnormalities were not associated with the duration or maximum amount of cocaine use during pregnancy.

conclusionNone of the infants had severe abnormalities. Detected abnormalities were not correlated with the duration or maximum amount of cocaine use. Given these findings, we feel that routine cranial ultrasonography in this population is not warranted.

Indexed as

Prenatal Exposure Delayed EffectsAbnormalities, Drug-InducedAdolescentAdultBrain DiseasesCocaine-Related DisordersFemaleHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesMaleMaternal-Fetal ExchangePregnancyProspective StudiesRisk Factors

Identifiers

PMID19099298
OpenAlexW2030431232

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.