ArticleJournal of lipid research2009
Plant phospholipid signaling: "in a nutshell".
Article in Journal of lipid research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.
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Who cites it
117 citing papers in PubMed, 285 citations in OpenAlex.
- Loss of AtPLC1 Impairs Salt-Alkali Tolerance via Disruption of Stomatal Regulation and Redox Homeostasis inPlants (Basel, Switzerland) · 2026Article
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- Omics approaches to investigate pre-symbiotic responses of the mycorrhizal fungus Tulasnella sp. SV6 to the orchid host Serapias vomeracea.Mycorrhiza · 2025Article
- Global profiling of CPL3-mediated alternative splicing reveals regulatory mechanisms of DGK5 in plant immunity and phosphatidic acid homeostasis.Genome biology · 2025Article
- Plant PI-PLC signaling in stress and development.Plant physiology · 2025Review
- Characterization and metabolomic profiling of endophytic bacteria isolated from Moringa oleifera and Piper betel leaves.Scientific reports · 2025Article
- Lesion mimic geneFrontiers in plant science · 2025Article
- Genome-wide identification of the PI-PLC gene family inFrontiers in plant science · 2025Article
- DArTseq-Based, High-Throughput Identification of Novel Molecular Markers for the Detection of Blackleg (International journal of molecular sciences · 2024Article
- Ectopic Expression of Distinct PLC Genes Identifies 'Compactness' as a Possible Architectural Shoot Strategy to Cope with Drought Stress.Plant & cell physiology · 2024Article
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- Physiological Analysis and Genetic Mapping of Short Hypocotyl Trait inInternational journal of molecular sciences · 2023Article
- Multiplexed Host-Induced Gene Silencing ofToxins · 2023Article
- RNA-seq profiling in leaf tissues of two soybean (Molecular breeding : new strategies in plant improvement · 2023Article
- Beneficial Microorganisms Improve Agricultural Sustainability under Climatic Extremes.Life (Basel, Switzerland) · 2023Review
- Burning questions for a warming and changing world: 15 unknowns in plant abiotic stress.The Plant cell · 2023Article
- Drought and heat stress mediated activation of lipid signaling in plants: a critical review.Frontiers in plant science · 2023Review
- Unraveling Genomic Regions Controlling Root Traits as a Function of Nitrogen Availability in the MAGIC Wheat Population WM-800.Plants (Basel, Switzerland) · 2022Article
57 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the discovery of the phosphoinositide/phospholipase C (PI/PLC) system in animal systems, we know that phospholipids are much more then just structural components of biological membranes. In the beginning, this idea was fairly straightforward. Receptor stimulation activates PLC, which hydrolyses phosphatidylinositol4,5-bisphosphate [PtdIns(4,5)P2] into two second messengers: inositol 1,4,5-trisphosphate (InsP3) and diacylglycerol (DG). While InsP3 difuses into the cytosol and triggers the release of calcium from an internal store via ligand-gated calcium channels, DG remains in the membrane where it recruits and activates members of the PKC family. The increase in calcium, together with the change in phosphorylation status, (in)activates a variety of protein targets, leading to a massive reprogramming, allowing the cell to appropriately respond to the extracellular stimulus. Later, it became obvious that not just PLC, but a variety of other phospholipid-metabolizing enzymes were activated, including phospholipase A, phospholipase D, and PI 3-kinase. More recently, it has become apparent that PtdIns4P and PtdIns(4,5)P2 are not just signal precursors but can also function as signaling molecules themselves. While plants contain most of the components described above, and evidence for their role in cell signaling is progressively increasing, major differences between plants and the mammalian paradigms exist. Below, these are described "in a nutshell."
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.