ReviewJournal of cellular biochemistry2009
Transplantation of human embryonic stem cell-derived endothelial cells for vascular diseases.
Review in Journal of cellular biochemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Up-regulation of Trim28 in pregnancy-induced hypertension is involved in the injury of human umbilical vein endothelial cells through the p38 signaling pathway.Histology and histopathology · 2024Article
- Comparative Study of Human Pluripotent Stem Cell-Derived Endothelial Cells in Hydrogel-Based Culture Systems.ACS omega · 2021Article
- Human Cell Modeling for Cardiovascular Diseases.International journal of molecular sciences · 2020Review
- Bioactive hydrogels for bone regeneration.Bioactive materials · 2018Review
- A Scalable and Efficient Bioprocess for Manufacturing Human Pluripotent Stem Cell-Derived Endothelial Cells.Stem cell reports · 2018Article
- Multiple therapeutic effect of endothelial progenitor cell regulated by drugs in diabetes and diabetes related disorder.Journal of translational medicine · 2017Review
- IGF-1 C Domain-Modified Hydrogel Enhances Cell Therapy for AKI.Journal of the American Society of Nephrology : JASN · 2016Article
- Directing human embryonic stem cells towards functional endothelial cells easily and without purification.Tissue engineering and regenerative medicine · 2016Article
- Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?EMBO molecular medicine · 2015Review
- Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment.Scientific reports · 2015Article
- Pluripotent Stem Cell Therapy in Ischemic Cardiovascular Disease.Acta Cardiologica Sinica · 2014Review
- Antitumor effects of CD40 ligand-expressing endothelial progenitor cells derived from human induced pluripotent stem cells in a metastatic breast cancer model.Stem cells translational medicine · 2014Article
- Tracking the Fate of Muscle-derived Stem Cells: an Insight into the Distribution and Mode of Action.Vascular specialist international · 2014Article
- Soluble factors secreted by differentiating embryonic stem cells stimulate exogenous cell proliferation and migration.Stem cell research & therapy · 2014Article
- Specialized mouse embryonic stem cells for studying vascular development.Stem cells and cloning : advances and applications · 2014Article
- Improved mesenchymal stem cell survival in ischemic heart through electroacupuncture.Chinese journal of integrative medicine · 2013Article
- High-purity enrichment of functional cardiovascular cells from human iPS cells.Cardiovascular research · 2012Article
- Bioengineering heart muscle: a paradigm for regenerative medicine.Annual review of biomedical engineering · 2011Article
- Bioluminescence reporter gene imaging characterize human embryonic stem cell-derived teratoma formation.Journal of cellular biochemistry · 2011Article
- Functional characterization of embryonic stem cell-derived endothelial cells.Journal of vascular research · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Using endothelial cells for therapeutic angiogenesis/vasculogenesis of ischemia diseases has led to exploring human embryonic stem cells (hESCs) as a potentially unlimited source for endothelial progenitor cells. With their capacity for self-renewal and pluripotency, hESCs and their derived endothelial cells (hESC-ECs) may be more advantageous than other endothelial cells obtained from diseased populations. However, hESC-ECs' poor differentiation efficiency and poorly characterized in vivo function after transplantation present significant challenges for their future clinical application. This review will focus on the differentiation pathways of hESCs and their therapeutic potential for vascular diseases, as well as the monitoring of transplanted cells' fate via molecular imaging. Finally, cell enhancement strategies to improve the engraftment efficiency of hESC-ECs will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.