ReviewEuropean journal of pediatrics2009
Saccharomyces boulardii in childhood.
Review in European journal of pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- The effect of Saccharomyces boulardii supplementation on Helicobacter pylori eradication in children: a systematic review and meta-analysis of Randomized controlled trials.BMC infectious diseases · 2023Pooled it
- Probiotic sepsis in preterm neonates-a systematic review.European journal of pediatrics · 2022Pooled it
- Systematic review and meta-analysis of Saccharomyces boulardii in adult patients.World journal of gastroenterology · 2010Pooled it
- Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia.BMJ paediatrics open · 2025Trial
- Saccharomyces boulardii CNCM I-745 plus sequential therapy for Helicobacter pylori infections: a randomized, open-label trial.European journal of clinical pharmacology · 2019Trial
- Trial
- Prophylactic Saccharomyces boulardii versus nystatin for the prevention of fungal colonization and invasive fungal infection in premature infants.European journal of pediatrics · 2013Trial
- Clinical efficacy comparison of Saccharomyces boulardii and yogurt fluid in acute non-bloody diarrhea in children: a randomized, controlled, open label study.The American journal of tropical medicine and hygiene · 2010Trial
- Article
- The Impact of Bioactive Molecules from Probiotics on Child Health: A Comprehensive Review.Nutrients · 2024Review
- Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens.Antibiotics (Basel, Switzerland) · 2023Review
- In Vitro Probitotic Evaluation ofFoods (Basel, Switzerland) · 2021Article
- Comparison of safety, effectiveness and serum inflammatory factor indexes ofTranslational pediatrics · 2021Article
- Application of Probiotic Yeasts onJournal of fungi (Basel, Switzerland) · 2020Review
- Efficacy of the Probiotic Probiotical Confirmed in Acute Gastroenteritis.Pediatric gastroenterology, hepatology & nutrition · 2020Article
- Trehalose Protects the Probiotic YeastJournal of microbiology and biotechnology · 2020Article
- Probiotics in pediatrics.Indian journal of pediatrics · 2015Article
- The Efficacy of Saccharomyces boulardii CNCM I-745 in Addition to Standard Helicobacter pylori Eradication Treatment in Children.Pediatric gastroenterology, hepatology & nutrition · 2015Article
- Co-production of bioethanol and probiotic yeast biomass from agricultural feedstock: application of the rural biorefinery concept.AMB Express · 2014Article
- Clinical practice: Helicobacter pylori infection in childhood.European journal of pediatrics · 2013Review
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionProbiotics are live microorganisms which confer a health benefit on the host. Saccharomyces boulardii, a yeast, has been found to be an effective probiotic in double-blind placebo-controlled randomized clinical studies. MATERIALS AND
methodsWe reviewed the established mechanisms of actions and clinical efficacy in children of S. boulardii.
conclusionsThe mechanisms of action of S. boulardii depend mainly on the inhibition of some bacterial toxins, anti-inflammatory effects, and on stimulating effects on the intestinal mucosa such as trophic effects on the brush border enzymes and immunostimulatory effects. At present, in pediatric populations, there is evidence that S. boulardii is beneficial for the treatment of acute gastroenteritis and the prevention of antibiotic-associated diarrhea. More data are needed in other indications such as traveller's diarrhea, Helicobacter pylori eradication, and inflammatory bowel disease. S. boulardii is a yeast strain that has been extensively studied in vitro and in vivo. Recent data have opened the door for new therapeutic indications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.