ArticlePLoS genetics2008
Sexually antagonistic "zygotic drive" of the sex chromosomes.
Article in PLoS genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed.
- Article
- Sexually antagonistic coevolution between the sex chromosomes ofProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Do sex chromosomes of snakes, monitor lizards, and iguanian lizards result from multiple fission of an "ancestral amniote super-sex chromosome"?Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2020Article
- Partial Amniote Sex Chromosomal Linkage Homologies Shared on Snake W Sex Chromosomes Support the Ancestral Super-Sex Chromosome Evolution in Amniotes.Frontiers in genetics · 2020Article
- Intragenomic Conflict and Immune Tolerance: Do Selfish X-Linked Alleles Drive Skewed X Chromosome Inactivation?Genome biology and evolution · 2018Article
- Genetic conflicts: the usual suspects and beyond.The Journal of experimental biology · 2017Review
- A Genealogical Look at Shared Ancestry on the X Chromosome.Genetics · 2016Article
- Genomic conflicts and sexual antagonism in human health: insights from oxytocin and testosterone.Evolutionary applications · 2015Review
- Human homosexuality: a paradigmatic arena for sexually antagonistic selection?Cold Spring Harbor perspectives in biology · 2015Review
- Sexually antagonistic zygotic drive: a new form of genetic conflict between the sex chromosomes.Cold Spring Harbor perspectives in biology · 2015Review
- Coadaptation and conflict, misconception and muddle, in the evolution of genomic imprinting.Heredity · 2014Review
- An X-linked sex ratio distorter in Drosophila simulans that kills or incapacitates both noncarrier sperm and sons.G3 (Bethesda, Md.) · 2014Article
- Genetics of dioecy and causal sex chromosomes in plants.Journal of genetics · 2014Review
- Genome-wide gene expression effects of sex chromosome imprinting in Drosophila.G3 (Bethesda, Md.) · 2014Article
- X- and Y-chromosome linked paternal effects on a life-history trait.Biology letters · 2012Article
- Article
- The emergence of human-evolutionary medical genomics.Evolutionary applications · 2011Article
- Empirical evidence for son-killing X chromosomes and the operation of SA-zygotic drive.PloS one · 2011Article
- The selfish grandma gene: the roles of the x-chromosome and paternity uncertainty in the evolution of grandmothering behavior and longevity.International journal of evolutionary biology · 2011Article
- Epigenetic effects of polymorphic Y chromosomes modulate chromatin components, immune response, and sexual conflict.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Genomic conflict is perplexing because it causes the fitness of a species to decline rather than improve. Many diverse forms of genomic conflict have been identified, but this extant tally may be incomplete. Here, we show that the unusual characteristics of the sex chromosomes can, in principle, lead to a previously unappreciated form of sexual genomic conflict. The phenomenon occurs because there is selection in the heterogametic sex for sex-linked mutations that harm the sex of offspring that does not carry them, whenever there is competition among siblings. This harmful phenotype can be expressed as an antagonistic green-beard effect that is mediated by epigenetic parental effects, parental investment, and/or interactions among siblings. We call this form of genomic conflict sexually antagonistic "zygotic drive", because it is functionally equivalent to meiotic drive, except that it operates during the zygotic and postzygotic stages of the life cycle rather than the meiotic and gametic stages. A combination of mathematical modeling and a survey of empirical studies is used to show that sexually antagonistic zygotic drive is feasible, likely to be widespread in nature, and that it can promote a genetic "arms race" between the homo- and heteromorphic sex chromosomes. This new category of genomic conflict has the potential to strongly influence other fundamental evolutionary processes, such as speciation and the degeneration of the Y and W sex chromosomes. It also fosters a new genetic hypothesis for the evolution of enigmatic fitness-reducing traits like the high frequency of spontaneous abortion, sterility, and homosexuality observed in humans.
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