Evidence map›Paper›PMID 19095140›Full record

ArticleJournal of the American College of Cardiology2008

Additional lipid lowering trials using surrogate measurements of atherosclerosis by carotid intima-media thickness: more clarity or confusion?

Evan A Stein

Registry-linked trialAbstract readCommentEditorial
PubMed Publisher
In one paragraph

Article in Journal of the American College of Cardiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01683656 (ER Niacin/Laropiprant Impact on Cardiovascular Markers and Atheroprogression in HIV-infected Individuals on cART), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01683656 phase4terminatedstarted 2012, after this paper: background citation

ER Niacin/Laropiprant Impact on Cardiovascular Markers and Atheroprogression in HIV-infected Individuals on cART

Ran2012Enrolled4Registered outcomes5Posted comparisons0ConditionsAtherosclerosis, HIVArmsNiacin/laropiprant, Placebo
Open the trial in the graph
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Lipid lowering and imaging protease activation in atherosclerosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Article
  2. Article
  3. Ezetimibe therapy: mechanism of action and clinical update.Vascular health and risk management · 2012
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Evan A Stein

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anticholesteremic AgentsAzetidinesBiomarkersCarotid ArteriesCarotid Artery DiseasesCholesterol, LDLDiabetes ComplicationsDiabetes Mellitus, Type 2Disease ProgressionDrug Therapy, CombinationEzetimibeHumansHydroxymethylglutaryl-CoA Reductase InhibitorsTunica IntimaTunica MediaAnticholesteremic AgentsAzetidinesBiomarkersCholesterol, LDLEzetimibeHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.