ReviewJournal of internal medicine2009
Mucosal T-cell responses to HIV: responding at the front lines.
Review in Journal of internal medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Article
- Innate and Adaptive Anti-SIV Responses in Macaque Semen: Implications for Infectivity and Risk of Transmission.Frontiers in immunology · 2020Article
- A pro-inflammatory CD8+ T-cell subset patrols the cervicovaginal tract.Mucosal immunology · 2019Article
- Article
- Intraepithelial γδ T cells remain increased in the duodenum of AIDS patients despite antiretroviral treatment.PloS one · 2012Article
- HIV infection and specific mucosal immunity: workshop 4B.Advances in dental research · 2011Article
- CD8(+)T-cell-mediated control of HIV-1 and SIV infection.Immunologic research · 2011Review
- Innate immunity including epithelial and nonspecific host factors: workshop 1B.Advances in dental research · 2011Article
- Characterization of an effective CTL response against HIV and SIV infections.Journal of biomedicine & biotechnology · 2011Review
- Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
- Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation.PLoS pathogens · 2010Article
- Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: implications for CD8 T-cell exhaustion.Journal of virology · 2010Article
- Mucosal immunology of the genital and gastrointestinal tracts and HIV-1 infection.Journal of reproductive immunology · 2009Review
- Pathogenic infection of Macaca nemestrina with a CCR5-tropic subtype-C simian-human immunodeficiency virus.Retrovirology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Mucosal surfaces of the body serve as the major portal of entry for human immunodeficiency virus (HIV). These tissues also house a majority of the body's lymphocytes, including the CD4(+) T cells that are the major cellular target for HIV infection. Mucosal surfaces are defended by innate and adaptive immune mechanisms, including secreted antibodies and CD8(+) cytotoxic T cells (CTL). CTL in mucosal lymphoid tissues may serve to limit viral replication, decreasing the host's viral burden as well as reducing the likelihood of sexual transmission to a naïve host. This review summarizes recent literature on HIV-specific T-cell responses in mucosal tissues, with an emphasis on the gastrointestinal tract.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.