ReviewNature reviews. Genetics2009
Detecting shared pathogenesis from the shared genetics of immune-related diseases.
Review in Nature reviews. Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 246 papers, 19 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
246 citing papers in PubMed, 19 syntheses or guidelines pooled it, 557 citations in OpenAlex.
- Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus.Nature communications · 2023Pooled it
- Identifying shared genetic loci and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies.Frontiers in immunology · 2023Pooled it
- Association between FAS gene -670 A/G and -1377 G/A polymorphisms and the risk of autoimmune diseases: a meta-analysis.Bioscience reports · 2020Pooled it
- Genome-wide meta-analysis reveals shared newAnnals of the rheumatic diseases · 2019Pooled it
- TIM-3 rs1036199 polymorphism increases susceptibility to autoimmune diseases: evidence based on 4200 subjects.Bioscience reports · 2018Pooled it
- Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations.Genome medicine · 2018Pooled it
- Biosemantics guided gene expression profiling of Sjögren's syndrome: a comparative analysis with systemic lupus erythematosus and rheumatoid arthritis.Arthritis research & therapy · 2017Pooled it
- Relationship of HLA-B*51 and HLA-B*52 alleles and TNF-α-308A/G polymorphism with susceptibility to Takayasu arteritis: a meta-analysis.Clinical rheumatology · 2017Pooled it
- Integrative analysis of genetic data sets reveals a shared innate immune component in autism spectrum disorder and its co-morbidities.Genome biology · 2016Pooled it
- Integrated Analyses of Gene Expression Profiles Digs out Common Markers for Rheumatic Diseases.PloS one · 2015Pooled it
- No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.Human molecular genetics · 2014Pooled it
- Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.Nature genetics · 2013Pooled it
- Pooled it
- Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases.BMC genomics · 2012Pooled it
- The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis.Genes and immunity · 2012Pooled it
- Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.PLoS genetics · 2012Pooled it
- Can genetic pleiotropy replicate common clinical constellations of cardiovascular disease and risk?PloS one · 2012Pooled it
- Abundant pleiotropy in human complex diseases and traits.American journal of human genetics · 2011Pooled it
- Pervasive sharing of genetic effects in autoimmune disease.PLoS genetics · 2011Pooled it
- Risk of Cancer in Patients with Rheumatoid Arthritis Compared with the General Population: A Nationwide Cohort Study in Lithuania.Medicina (Kaunas, Lithuania) · 2026Article
186 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent genetic studies have revealed shared immunological mechanisms in several immune-related disorders that further our understanding of the development and concomitance of these diseases. Our Review focuses on these shared aspects, using the novel findings of recently performed genome-wide association studies and non-synonymous SNP scans as a starting point. We discuss how identifying new genes that are associated with more than one autoimmune or chronic inflammatory disorder could explain the genetic basis of the shared pathogenesis of immune-related diseases. This analysis helps to highlight the key molecular pathways that are involved in these disorders and the potential roles of novel genes in immune-related diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.