ReviewJournal of endocrinological investigation2008
Cardiovascular aspects of primary hyperparathyroidism.
Review in Journal of endocrinological investigation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Changes in vascular structure and function in primary hyperparathyroidism: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Risk of Malignant Neoplasm in Patients with Primary Hyperparathyroidism: A Systematic Review and Meta-analysis.Calcified tissue international · 2024Pooled it
- Pooled it
- Cardiovascular Alterations in Primary Hyperparathyroidism: Associations with Risk Profile, Cardiac Structure, and Function.Journal of clinical medicine · 2026Article
- Heart as white as stone, reborn: an unusual case report of idiopathic myocardial calcifications leading to end-stage heart failure and cardiac transplantation.European heart journal. Case reports · 2025Article
- Analysis of Clinical and Biochemical Parameters and the Effectiveness of Surgical Treatment in Patients with Primary Hyperparathyroidism: A Single-Center Study.Journal of clinical medicine · 2025Article
- Assessing and Managing Primary Hyperparathyroidism and Fracture Risk in England: A Survey of Medical Professionals.Journal of the Endocrine Society · 2025Article
- Normocalcemic primary hyperparathyroidism is not associated with cardiometabolic alterations.Endocrine · 2024Article
- Carotid Intima-Media Thickness in Surgically or Conservatively Managed Patients With Primary Hyperparathyroidism.The Journal of clinical endocrinology and metabolism · 2024Article
- Primary Hyperparathyroidism Is Associated With Shorter QTc Intervals, but Not Arrhythmia.The Journal of clinical endocrinology and metabolism · 2022Article
- Serum Calcium Predicts Cognitive Decline and Clinical Progression of Alzheimer's Disease.Neurotoxicity research · 2021Article
- Long-term therapeutic outcomes of papillary thyroid carcinoma with concomitant hyperparathyroidism: A single center case-control study.Biomedical journal · 2020Article
- Primary hyperparathyroidism.Nature reviews. Endocrinology · 2018Review
- Article
- Association between parathyroid hormone levels and the extensiveness of coronary artery disease.Anatolian journal of cardiology · 2016Article
- Observational
- Cardiovascular risk and metabolic syndrome in primary hyperparathyroidism and their correlation to different clinical forms.Endocrine · 2014Article
- Medial vascular calcification revisited: review and perspectives.European heart journal · 2014Review
- Potential pathophysiological role for the vitamin D deficiency in essential hypertension.World journal of cardiology · 2014Review
- Association between serum 25-hydroxyvitamin D level and subclinical cardiovascular disease in primary hyperparathyroidism.The Journal of clinical endocrinology and metabolism · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Data concerning the cardiovascular manifestations of primary hyperparathyroidism (PHPT) are inconsistent, which is due, in part, to the decrease in disease severity over the last several decades. In areas where patients tend to be more symptomatic, data support the presence of cardiovascular findings including myocardial and vascular calcification as well as increased cardiovascular mortality. Data from the cohorts in whom the disease is characterized by mild hypercalcemia, suggest that clinically overt cardiovascular manifestations are unusual in PHPT. Recent data, however, support the presence of subtle cardiovascular manifestations in mild disease, such as changes in endothelial function as well as increased vascular stiffness and perhaps diastolic dysfunction. Left ventricular hypertrophy is a more consistent finding across a spectrum of disease severity, though this finding may be related to hypertension, which has long been associated with PHPT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.