ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2008
Region-specific spike-frequency acceleration in layer 5 pyramidal neurons mediated by Kv1 subunits.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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Who cites it
46 citing papers in PubMed.
- Article
- Distinctive physiology of molecularly identified medium spiny neurons in the macaque putamen.Cell reports · 2024Article
- Areal specializations in the morpho-electric and transcriptomic properties of primate layer 5 extratelencephalic projection neurons.Cell reports · 2024Article
- Adenosinergic Modulation of Layer 6 Microcircuitry in the Medial Prefrontal Cortex Is Specific to Presynaptic Cell Type.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Fractional order memcapacitive neuromorphic elements reproduce and predict neuronal function.Scientific reports · 2024Article
- Evaluation of advances in cortical development using model systems.Developmental neurobiology · 2022Review
- Kv2.1 Potassium Channels Regulate Repetitive Burst Firing in Extratelencephalic Neocortical Pyramidal Neurons.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Article
- A repeated molecular architecture across thalamic pathways.Nature neuroscience · 2019Article
- Characterization of functional subgroups among genetically identified cholinergic neurons in the pedunculopontine nucleus.Cellular and molecular life sciences : CMLS · 2019Article
- Viral strategies for targeting cortical circuits that control cocaine-taking and cocaine-seeking in rodents.Pharmacology, biochemistry, and behavior · 2018Review
- Functional roles of Kv1-mediated currents in genetically identified subtypes of pyramidal neurons in layer 5 of mouse somatosensory cortex.Journal of neurophysiology · 2018Article
- Specialized Subpopulations of Deep-Layer Pyramidal Neurons in the Neocortex: Bridging Cellular Properties to Functional Consequences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Review
- Morphological and Functional Characterization of Non-fast-Spiking GABAergic Interneurons in Layer 4 Microcircuitry of Rat Barrel Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
- Chronic Stress Reduces Nectin-1 mRNA Levels and Disrupts Dendritic Spine Plasticity in the Adult Mouse Perirhinal Cortex.Frontiers in cellular neuroscience · 2018Article
- Marked bias towards spontaneous synaptic inhibition distinguishes non-adapting from adapting layer 5 pyramidal neurons in the barrel cortex.Scientific reports · 2017Article
- Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- A Mammalian enhancer trap resource for discovering and manipulating neuronal cell types.eLife · 2016Article
- Power-Law Dynamics of Membrane Conductances Increase Spiking Diversity in a Hodgkin-Huxley Model.PLoS computational biology · 2016Article
- Enhanced Sensitivity to Rapid Input Fluctuations by Nonlinear Threshold Dynamics in Neocortical Pyramidal Neurons.PLoS computational biology · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Separation of the cortical sheet into functionally distinct regions is a hallmark of neocortical organization. Cortical circuit function emerges from afferent and efferent connectivity, local connectivity within the cortical microcircuit, and the intrinsic membrane properties of neurons that comprise the circuit. While localization of functions to particular cortical areas can be partially accounted for by regional differences in both long range and local connectivity, it is unknown whether the intrinsic membrane properties of cortical cell types differ between cortical regions. Here we report the first example of a region-specific firing type in layer 5 pyramidal neurons, and show that the intrinsic membrane and integrative properties of a discrete subtype of layer 5 pyramidal neurons differ between primary motor and somatosensory cortices due to region- and cell-type-specific Kv1 subunit expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.