ArticleJournal of virology2009
Genome comparison of a nonpathogenic myxoma virus field strain with its ancestor, the virulent Lausanne strain.
Article in Journal of virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Review
- Enrichment and Reduction of Microsatellite Regions in the Myxoma Virus Genome Following Species Jump to the Iberian Hare (Transboundary and emerging diseases · 2026Article
- A Quadruplex qPCR for Detection and Differentiation of Classic and Natural Recombinant Myxoma Virus Strains of Leporids.International journal of molecular sciences · 2021Article
- Punctuated Evolution of Myxoma Virus: Rapid and Disjunct Evolution of a Recent Viral Lineage in Australia.Journal of virology · 2019Article
- Reverse Engineering Field Isolates of Myxoma Virus Demonstrates that Some Gene Disruptions or Losses of Function Do Not Explain Virulence Changes Observed in the Field.Journal of virology · 2017Article
- Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia.PLoS pathogens · 2017Article
- Genetic Variability of Myxoma Virus Genomes.Journal of virology · 2017Article
- Review
- Viral biocontrol: grand experiments in disease emergence and evolution.Trends in microbiology · 2015Review
- Article
- Poxviruses and the evolution of host range and virulence.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014Review
- Genome scale evolution of myxoma virus reveals host-pathogen adaptation and rapid geographic spread.Journal of virology · 2013Article
- Comparative analysis of the complete genome sequence of the California MSW strain of myxoma virus reveals potential host adaptations.Journal of virology · 2013Article
- Myxoma virus M064 is a novel member of the poxvirus C7L superfamily of host range factors that controls the kinetics of myxomatosis in European rabbits.Journal of virology · 2012Article
- Evolutionary history and attenuation of myxoma virus on two continents.PLoS pathogens · 2012Article
- The current status and future directions of myxoma virus, a master in immune evasion.Veterinary research · 2011Review
- Genome sequence of SG33 strain and recombination between wild-type and vaccine myxoma viruses.Emerging infectious diseases · 2011Article
- Molecular characterisation of virulence graded field isolates of myxoma virus.Virology journal · 2010Article
- Detection of myxoma viruses encoding a defective M135R gene from clinical cases of myxomatosis; possible implications for the role of the M135R protein as a virulence factor.Virology journal · 2010Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the best-studied examples of host-virus coevolution is the release of myxoma virus (MV) for biological control of European rabbits in Australia and Europe. To investigate the genetic basis of MV adaptation to its new host, we sequenced the genome of 6918, an attenuated Spanish field strain, and compared it with that of Lausanne, the strain originally released in Europe in 1952. Although isolated 43 years apart, the genomes were highly conserved (99.95% identical). Only 32 of the 159 MV predicted proteins revealed amino acid changes. Four genes (M009L, M036L, M135R, and M148R) in 6918 were disrupted by frameshift mutations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.