Evidence map›Paper›PMID 19091604›Full record

ArticleOsteoarthritis and cartilage2009

A 5 year prospective study of patient-relevant outcomes after total knee replacement.

A-K Nilsdotter, S Toksvig-Larsen, E M Roos

2 registry-linked trialsOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Osteoarthritis and cartilage, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01826305 naterminatednot on this mapstarted 2014, after this paper: background citation

Independent Exercise Compared With Formal Rehabilitation Following Primary Total Knee Replacement

TypeinterventionalSponsorUniversity of California, San FranciscoRan2014 to 2015Enrolled23ConditionsRecovery Following Primary Total Knee ArthroplastyArmsFormal Rehabilitation Therapy, Independent Exercise Cohort
NCT07494838 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success

TypeinterventionalSponsorLucas R. Cusumano, MDRan2026 to 2027Enrolled25ConditionsKnee Osteoarthritis, Knee Discomfort, Knee Pain Chronic, Knee Swelling PainArmsEmbolization
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 167 citations in OpenAlex.

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  3. A new methodology for patient education in total knee arthroplasty: a randomized controlled trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2022
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

A-K NilsdotterResearch and Development Department, Central Hospital, Halmstad, Sweden. Anna.Nilsdotter@lthalland.se
S Toksvig-Larsen
E M Roos
Lund University · SEUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo prospectively describe self-reported outcomes up to 5 years after total knee replacement (TKR) in Osteoarthritis (OA) and to study which patient-relevant factors may predict outcomes for pain and physical function (PF).

methods102 consecutive patients with knee OA, 63 women and 39 men, mean age 71 (51-86) assigned for TKR at the Department of Orthopaedics at Lund University Hospital were included in the study. The self-administered questionnaires Knee injury and Osteoarthritis Outcome Score (KOOS) and SF-36 were mailed preoperatively and 6 months, 12 months and at 5 years postoperatively.

resultsResponse rate at 5 years was 86%. At 6 months significant improvement was seen in all KOOS and SF-36 scores (P<0.001). The percentage of patients performing more demanding functions related to sports and recreation increased postoperatively. The best postoperative result was reported at the 1 year follow-up. Compared to the 1 year follow-up, a significant (P<or=0.01) decline was seen at 5 years in the KOOS subscale activity of daily living (ADL) function (82-73) and the SF-36 subscale bodily pain (72-63), PF (61-51) and vitality (69-59). Patients who scored in the lowest quartile preoperatively in the KOOS subscales pain and ADL made the greatest improvements to 1 year (18-82, 22-80) but also declined the most from 12 months to 5 years (82-72, 80-66). Being 10 years older pre-operatively predicted 5-7 points worse scores in KOOS pain and KOOS symptoms at 1 and 5 years. When adjusted for age, sex and comorbid conditions, pre-operative SF-36 scores did not predict postoperative KOOS pain or PF scores.

conclusionCompared to preoperatively, a significant improvement was still seen 5 years postoperatively. However, the best result was reported at 1 year, indicating a decline from 1 to 5 years after TKR. To fully evaluate the results of TKR with regard to pain and PF, follow-ups longer than 2 years are needed, and items of more demanding PFs should be included. Older age to some extent predicted more postoperative pain and other symptoms, however, no predictors of postoperative PF were found, indicating the difficulty of determining preoperatively who will benefit more or less from the procedure.

Indexed as

Activities of Daily LivingAgedAged, 80 and overArthroplasty, Replacement, KneeFemaleHumansMaleMiddle AgedOsteoarthritis, KneePainPatient SatisfactionProspective StudiesSurveys and QuestionnairesTime FactorsTreatment Outcome

Identifiers

PMID19091604
OpenAlexW2024594564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.