ArticleNeurobiology of aging2010
Coronary heart disease is associated with non-amnestic mild cognitive impairment.
Article in Neurobiology of aging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
69 citing papers in PubMed, 3 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- The Relationship of Coronary Artery Calcium and Clinical Coronary Artery Disease with Cognitive Function: A Systematic Review and Meta-Analysis.Journal of atherosclerosis and thrombosis · 2020Pooled it
- The Association between the Mediterranean Dietary Pattern and Cognitive Health: A Systematic Review.Nutrients · 2017Pooled it
- Coronary heart disease and risk for cognitive impairment or dementia: Systematic review and meta-analysis.PloS one · 2017Pooled it
- Problem adaptation therapy for older adults with major depression and cognitive impairment: a randomized clinical trial.JAMA psychiatry · 2015Trial
- Cardiac disease associated with increased risk of nonamnestic cognitive impairment: stronger effect on women.JAMA neurology · 2013Trial
- Oxidative stress, aging, metabolism, SIRT1, and the gut microbiota: the neurocardiac basis of cognitive loss.Medical gas research · 2027Review
- Dementia Risk in the Decade Before and After Coronary Heart Disease Diagnosis: Hybrid Case-Control and Cohort Study.Journal of the American Heart Association · 2026Article
- Running out the clock: Circadian rhythm dysfunction in cognitive disease.International review of neurobiology · 2026Review
- Predictive model of neurocognitive functioning after acute coronary syndrome. A machine learning approach.Journal of cardiovascular and thoracic research · 2025Article
- Associations of ischemic heart disease with brain glymphatic MRI indices and risk of Alzheimer's disease.The journal of prevention of Alzheimer's disease · 2025Article
- Article
- Communication Regarding the Myocardial Ischemia/Reperfusion and Cognitive Impairment: A Narrative Literature Review.Journal of Alzheimer's disease : JAD · 2024Review
- Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis.Brain structure & function · 2024Article
- Review
- Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment.Acta neuropathologica communications · 2023Review
- Racial/Ethnic Disparities in the Alzheimer's Disease Link with Cardio and Cerebrovascular Diseases, Based on Hawaii Medicare Data.Journal of Alzheimer's disease reports · 2023Article
- Midlife Vascular Factors and Prevalence of Mild Cognitive Impairment in Late-Life in Mexico.Journal of the International Neuropsychological Society : JINS · 2022Article
- Factors influencing cognitive performance after 1-year treatment with direct oral anticoagulant in patients with atrial fibrillation and previous ischemic stroke: a pilot study.Journal of thrombosis and thrombolysis · 2021Article
- Glutathione Peroxidase Activity Is Altered in Vascular Cognitive Impairment-No Dementia and Is a Potential Marker for Verbal Memory Performance.Journal of Alzheimer's disease : JAD · 2021Article
- A Review of Acute Coronary Syndrome and its Potential Impact on Cognitive Function.Global heart · 2021Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The progression of amnestic mild cognitive impairment (a-MCI) to Alzheimer's disease and hypothesized progression of non-amnestic mild cognitive impairment (na-MCI) to non-degenerative or vascular dementias suggest etiologic differences. We examined the association between coronary heart disease (CHD) and mild cognitive impairment (MCI) subtypes in a population-based cohort. Participants (n=1969; aged 70-89 years) were evaluated using the Clinical Dementia Rating Scale, a neurological examination, and neuropsychological testing for diagnoses of normal cognition, MCI, or dementia. CHD was defined as a history of myocardial infarction, angina, angiographic coronary stenosis, or coronary revascularization and ascertained by participant interview and from medical records. CHD was significantly associated with na-MCI (OR=1.93; 95% CI=1.22-3.06) but not with a-MCI (OR=0.94; 95% CI=0.69-1.28). In contrast, ApoE ɛ4 allele was significantly associated with a-MCI (OR=1.75; 95% CI=1.28-2.41), but not with na-MCI (OR=1.17; 95% CI=0.69-2.00). The association of CHD with prevalent na-MCI but not with a-MCI suggests that CHD and na-MCI may have similar underlying etiologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.