Evidence map›Paper›PMID 19091006›Full record

ReviewBreast cancer research : BCR2008

Mechanisms of metastasis.

Kent W Hunter, Nigel P S Crawford, Jude Alsarraj

Abstract readReview
In one paragraph

Review in Breast cancer research : BCR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Noncoding RNAs, Vital Players in Breast Cancer Metastasis.Breast cancer (Dove Medical Press) · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
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  16. Regional anesthesia is associated with improved metastasis free survival after surgical resection of bone sarcomas.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Article

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kent W HunterLaboratory of Cancer Biology and Genetics, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892-4264, USA. hunterk@mail.nih.gov
Nigel P S Crawford
Jude Alsarraj

Funding

GENETIC MODIFIERS OF MAMMARY CANCER INITIATION/ PROGRESSZ01CP010146 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI HUNTER, KENT WILLIAM · 2000 to 2008
$3.3M
Genetic Modifiers of Intitiation and Progression of Mammary CancerZIACP010146 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI HUNTER, KENT WILLIAM · 2009 to 2009
$1.7M
Intramural NIH HHS
6 · The paper itself

Abstract

Metastasis is an enormously complex process that remains to be a major problem in the management of cancer. The fact that cancer patients might develop metastasis after years or even decades from diagnosis of the primary tumor makes the metastatic process even more complex. Over the years many hypotheses were developed to try to explain the inefficiency of the metastatic process, but none of these theories completely explains the current biological and clinical observations. In this review we summarize some of the proposed models that were developed in attempt to understand the mechanisms of tumor dissemination and colonization as well as metastatic progression.

Indexed as

AnimalsDisease ProgressionGenes, Tumor SuppressorHumansNeoplasm MetastasisNeoplasms

Identifiers

PMID19091006
PMCPMC2605099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.