ReviewBreast cancer research : BCR2008
Genetic counselling and testing for inherited gene mutations in newly diagnosed patients with breast cancer: a review of the existing literature and a proposed research agenda.
Review in Breast cancer research : BCR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed.
- Impact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial.British journal of cancer · 2014Trial
- Trial
- Germline testing, access to genetic counseling, and treatment implications in advanced breast cancer.Annals of medicine and surgery (2012) · 2026Article
- Article
- Stakeholder attitudes towards establishing a national genomics registry of inherited cancer predisposition: a qualitative study.Journal of community genetics · 2022Article
- A 23-gene prognostic classifier for prediction of recurrence and survival for Asian breast cancer patients.Bioscience reports · 2020Article
- Development of Breast Cancer Choices: a decision support tool for young women with breast cancer deciding whether to have genetic testing for BRCA1/2 mutations.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Patients' Views of Treatment-Focused Genetic Testing (TFGT): Some Lessons for the Mainstreaming of BRCA1 and BRCA2 Testing.Journal of genetic counseling · 2018Article
- Paclitaxel inhibits breast cancer metastasis via suppression of Aurora kinase-mediated cofilin-1 activity.Experimental and therapeutic medicine · 2018Article
- Cancer Genetic Counselors' Current Practices and Attitudes Related to the Use of Tumor Profiling.Journal of genetic counseling · 2017Article
- Comparison between CaGene 5.1 and 6.0 for BRCA1/2 mutation prediction: a retrospective study of 150 BRCA1/2 genetic tests in 517 families with breast/ovarian cancer.Journal of human genetics · 2017Article
- When knowledge of a heritable gene mutation comes out of the blue: treatment-focused genetic testing in women newly diagnosed with breast cancer.European journal of human genetics : EJHG · 2016Article
- Timing of risk reducing mastectomy in breast cancer patients carrying a BRCA1/2 mutation: retrospective data from the Dutch HEBON study.Familial cancer · 2015Article
- Health professionals' evaluation of delivering treatment-focused genetic testing to women newly diagnosed with breast cancer.Familial cancer · 2015Article
- Improving referral for genetic risk assessment in ovarian cancer using an electronic medical record system.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2014Article
- Specific psychosocial issues of individuals undergoing genetic counseling for cancer - a literature review.Journal of genetic counseling · 2014Review
- Genetic risk assessment for women with epithelial ovarian cancer: referral patterns and outcomes in a university gynecologic oncology clinic.Journal of genetic counseling · 2013Article
- Short-term psychological impact of the BRCA1/2 test result in women with breast cancer according to their perceived probability of genetic predisposition to cancer.British journal of cancer · 2013Article
- Are we being overly cautious? A qualitative inquiry into the experiences and perceptions of treatment-focused germline BRCA genetic testing amongst women recently diagnosed with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2012Article
- The evolution of personalized cancer genetic counseling in the era of personalized medicine.Familial cancer · 2012Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many women newly diagnosed with breast cancer and with a strong family history of breast cancer are referred to a family cancer service for genetic counselling and for consideration of genetic testing for germline mutations in cancer predisposition genes following completion of their cancer treatment. However, there is growing evidence that mutation status may influence treatment recommendations, and that there may be benefits in having 'treatment-focused genetic counselling and testing' available shortly after cancer diagnosis. This article reviews the literature that could inform the development of treatment-focused genetic counselling and testing, including: the rationale for genetic testing to aid with treatment decisions; the potential benefits of using mutation or risk status to tailor management; the criteria that may be used to identify patients most likely to carry germline mutations; and the evidence regarding women's decision-making regarding treatment-focused genetic counselling and testing and the associated psychological impact.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.