ArticlePediatric nephrology (Berlin, Germany)2009
Renal manifestations in toddlers with Takayasu's arteritis and malignant hypertension.
Article in Pediatric nephrology (Berlin, Germany), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Real-World Biomarkers for Pediatric Takayasu Arteritis.International journal of molecular sciences · 2024Pooled it
- Wind of Change in the Treatment of Childhood-Onset Takayasu Arteritis: a Systematic Review.Current rheumatology reports · 2021Pooled it
- Biologics for childhood systemic vasculitis.Pediatric nephrology (Berlin, Germany) · 2019Review
- Aggressive progression of Takayasu's arteritis in infancy: a case report.Acta clinica Croatica · 2019Article
- Takayasu arteritis with an initial presentation of chronic monoarthritis mimicking oligoarticular juvenile idiopathic arthritis.Pediatric reports · 2018Article
- A case of secondary focal segmental glomerulosclerosis associated with malignant hypertension.CEN case reports · 2013Article
- Do classification criteria of Takayasu arteritis misdiagnose children with fibromuscular dysplasia?Pediatric nephrology (Berlin, Germany) · 2010Article
- Angioplasty for pediatric renovascular hypertension: a 13-year experience.Diagnostic and interventional radiology (Ankara, Turkey)Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three children under the age of 3 years presented with malignant hypertension, proteinuria, and acute kidney injury. Takayasu's arteritis was diagnosed on the basis of clinical symptoms of weight loss and low grade fever in conjunction with elevated sedimentation rate and radiographic evidence of aortic and renal artery stenosis. One patient had a renal biopsy which showed arteriolar sclerosis and focal glomerulosclerosis. All three patients required multiple antihypertensive agents, ultimately including angiotensin receptor blockers and/or angiotensin converting enzyme inhibitors. The vasculitis was treated with pulse corticosteroids followed by cyclophosphamide in one patient and mycophenolate mofetil as maintenance therapy in all. Follow-up has ranged from 2 to 8 years. Although global renal function has normalized in each patient, two have unilateral non-function of one kidney. The last patient has persistent aortic and renal artery stenosis with complex collateralization requiring ongoing medical and anticipated surgical management.
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