ReviewJournal of applied oral science : revista FOB
Slow-release fluoride devices: a literature review.
Review in Journal of applied oral science : revista FOB. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 65 citations in OpenAlex.
- The effect of fluoride slow-releasing devices on fluoride in plaque biofilms and saliva: a randomised controlled trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2011Trial
- The Morphological, Thermal, and Mechanical Properties of Glass Ionomer Modified Polylactic Acid Polymer.International journal of dentistry · 2026Article
- Case Study of a Broken Instrument in a Primary Tooth and Literature Review.Children (Basel, Switzerland) · 2025Article
- Intraoral medical devices for sustained drug delivery.Clinical oral investigations · 2023Review
- 3D hydrogel/ bioactive glass scaffolds in bone tissue engineering: Status and future opportunities.Heliyon · 2023Review
- Clinical and Antimicrobial Evaluation ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Emerging Applications of Drug Delivery Systems in Oral Infectious Diseases Prevention and Treatment.Molecules (Basel, Switzerland) · 2020Review
- Dose-response evaluation of a copaiba-containing varnish against streptococcus mutans in vivo.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019Article
- 3D printing of a wearable personalized oral delivery device: A first-in-human study.Science advances · 2018Article
- The history of public health use of fluorides in caries prevention.Zdravstveno varstvo · 2017Article
- Prevention of enamel demineralization with a novel fluoride strip: enamel surface composition and depth profile.Scientific reports · 2015Article
- Propolis--based chitosan varnish: drug delivery, controlled release and antimicrobial activity against oral pathogen bacteria.BMC complementary and alternative medicine · 2014Article
- Preparation and optimization of calcium fluoride particles for dental applications.Journal of materials science. Materials in medicine · 2014Article
- Iatrogenic possibilities of orthodontic treatment and modalities of prevention.Journal of orthodontic science · 2013Review
- Dental caries: A complete changeover, PART III: Changeover in the treatment decisions and treatments.Journal of conservative dentistry : JCD · 2010Article
- Novel technologies for the prevention and treatment of dental caries: a patent survey.Expert opinion on therapeutic patents · 2010Review
- A review of slow-release fluoride devices.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2009Review
- In vitro remineralization of enamel by polymeric amorphous calcium phosphate composite: quantitative microradiographic study.Dental materials : official publication of the Academy of Dental Materials · 2009Article
- Prevention and Treatment of White Spot Lesions in Orthodontic Patients.Contemporary clinical dentistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the prevalence of caries has decreased dramatically over the past decades, it has become a polarised disease, with most of subjects presenting low caries levels and few individuals accounting for most of the caries affected surfaces. Thus it become evident for the need of clinical approaches directed at these high-risk patients, in order to overcome problems related to compliance and low attendance at dental care centres. Slow-release fluoride devices were developed based on the inverse relationship existing between intra-oral fluoride levels and dental caries experience. The two main types of slow-release devices - copolymer membrane type and glass bead - are addressed in the present review. A substantial number of studies have demonstrated that these devices are effective in raising intra-oral F concentrations at levels able to reduce enamel solubility, resulting in a caries-protective effect. Studies in animals and humans demonstrated that the use of these devices was able to also protect the occlusal surfaces, not normally protected by conventional fluoride regimens. However, retention rates have been shown to be the main problem related to these devices and still requires further improvements. Although the results of these studies are very promising, further randomised clinical trials are needed in order to validate the use of these devices in clinical practice. The concept of continuously providing low levels of intra-oral fluoride has great potential for caries prevention in high caries-risk groups.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.