ArticleDose-response : a publication of International Hormesis Society2008
It's time for a new low-dose-radiation risk assessment paradigm--one that acknowledges hormesis.
Article in Dose-response : a publication of International Hormesis Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- PLGA-Based Curcumin Delivery System: An Interesting Therapeutic Approach in the Treatment of Alzheimer's Disease.Current neuropharmacology · 2022Review
- Review
- Cancer immunotherapy: how low-level ionizing radiation can play a key role.Cancer immunology, immunotherapy : CII · 2017Review
- Gamma radiation at a human relevant low dose rate is genotoxic in mice.Scientific reports · 2016Article
- Novel acyclic nucleotide analogues GS-343074 and GS-424044 demonstrate antiproliferative and pro-apoptotic activity in canine neoplastic cell lines.Veterinary and comparative oncology · 2015Article
- Radiation-hormesis phenotypes, the related mechanisms and implications for disease prevention and therapy.Journal of cell communication and signaling · 2014Article
- Remedy for radiation fear - discard the politicized science.Dose-response : a publication of International Hormesis Society · 2014Article
- Small γ-Ray Doses Prevent Rather than Increase Lung Tumors in Mice.Dose-response : a publication of International Hormesis Society · 2012Article
- Shifting the paradigm in radiation safety.Dose-response : a publication of International Hormesis Society · 2012Article
- Improving the scientific foundations for estimating health risks from the Fukushima incident.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders.Antioxidants & redox signaling · 2010Review
- Commentary on Using LNT for Radiation Protection and Risk Assessment.Dose-response : a publication of International Hormesis Society · 2010Article
- Radiation hormesis: historical perspective and implications for low-dose cancer risk assessment.Dose-response : a publication of International Hormesis Society · 2010Article
- The dose window for radiation-induced protective adaptive responses.Dose-response : a publication of International Hormesis Society · 2009Article
- Hormesis: a conversation with a critic.Environmental health perspectives · 2009Article
- How reliable are the risk estimates for X-ray examinations in forensic age estimations? A safety update.International journal of legal medicine · 2009Article
- Low-dose-radiation stimulated natural chemical and biological protection against lung cancer.Dose-response : a publication of International Hormesis Society · 2008Article
- Evidence for radiation hormesis after in vitro exposure of human lymphocytes to low doses of ionizing radiation.Dose-response : a publication of International Hormesis Society · 2008Article
- Some Epidemiologic Studies of Low-Dose-Radiation Cancer Risks Are Misinforming.Dose-response : a publication of International Hormesis SocietyArticle
- Health-Risk-Model Idolization Is Unscientific.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current system of radiation protection for humans is based on the linear-no-threshold (LNT) risk-assessment paradigm. Perceived harm to irradiated nuclear workers and the public is mainly reflected through calculated hypothetical increased cancers. The LNT-based system of protection employs easy-to-implement measures of radiation exposure. Such measures include the equivalent dose (a biological-damage-potential-weighted measure) and the effective dose (equivalent dose multiplied by a tissue-specific relative sensitivity factor for stochastic effects). These weighted doses have special units such as the sievert (Sv) and millisievert (mSv, one thousandth of a sievert). Radiation-induced harm is controlled via enforcing exposure limits expressed as effective dose. Expected cancer cases can be easily computed based on the summed effective dose (person-sievert) for an irradiated group or population. Yet the current system of radiation protection needs revision because radiation-induced natural protection (hormesis) has been neglected. A novel, nonlinear, hormetic relative risk model for radiation-induced cancers is discussed in the context of establishing new radiation exposure limits for nuclear workers and the public.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.