ArticleReproductive sciences (Thousand Oaks, Calif.)2008
The expression and ovarian steroid regulation of endometrial micro-RNAs.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 82 citations in OpenAlex.
- Assessment ofInternational journal of molecular sciences · 2023Article
- Uterus proliferative period ceRNA network of Yunshang black goat reveals candidate genes on different kidding number trait.Frontiers in endocrinology · 2023Article
- MicroRNA‑16 inhibits endometrial stromal cell migration and invasion through suppression of the inhibitor of nuclear factor‑κB kinase subunit β/nuclear factor‑κB pathway.International journal of molecular medicine · 2020Article
- Redox regulation of microRNAs in endometriosis-associated pain.Redox biology · 2017Article
- Non-coding RNAs in Uterine Development, Function and Disease.Advances in experimental medicine and biology · 2016Review
- MicroRNA Profiles in Spontaneous Decidualized Menstrual Endometrium and Early Pregnancy Decidua with Successfully Implanted Embryos.PloS one · 2016Article
- Systematic enrichment analysis of microRNA expression profiling studies in endometriosis.Iranian journal of basic medical sciences · 2015Review
- Identification and characterization of progesterone- and estrogen-regulated MicroRNAs in mouse endometrial epithelial cells.Reproductive sciences (Thousand Oaks, Calif.) · 2015Article
- Update on Biomarkers for the Detection of Endometriosis.BioMed research international · 2015Review
- MicroRNA-542-3p suppresses cell growth of gastric cancer cells via targeting oncogene astrocyte-elevated gene-1.Medical oncology (Northwood, London, England) · 2015Article
- MicroRNAs, immune cells and pregnancy.Cellular & molecular immunology · 2014Review
- High-throughput sequencing approach uncovers the miRNome of peritoneal endometriotic lesions and adjacent healthy tissues.PloS one · 2014Article
- MicroRNAs in endometrial cancer.International journal of clinical oncology · 2013Review
- Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis.Human reproduction (Oxford, England) · 2013Article
- An induction of microRNA, miR-7 through estrogen treatment in breast carcinoma.Journal of translational medicine · 2012Article
- MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression.Oncogene · 2012Article
- MiR-199a attenuates endometrial stromal cell invasiveness through suppression of the IKKβ/NF-κB pathway and reduced interleukin-8 expression.Molecular human reproduction · 2012Article
- MicroRNA 135 regulates HOXA10 expression in endometriosis.The Journal of clinical endocrinology and metabolism · 2011Article
- Minireview: The roles of small RNA pathways in reproductive medicine.Molecular endocrinology (Baltimore, Md.) · 2011Review
- Genomic features and computational identification of human microRNAs under long-range developmental regulation.BMC genomics · 2011Article
Corrections and comments
- Retraction · 2014-08-26Ethical Violations by Author · Falsification/Fabrication of Data · Investigation by Company/Institution · Investigation by ORI · · Nasser Chegini has finding of misconduct: https://ori.hhs.gov/content/case-summary-chegini-nasser
- Commented on by
- RetractedRetraction.2014
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
MicroRNAs (miRNAs) which regulate gene expression stability displayed an aberrant expression profile in ectopic endometrium (ECE) as compared to eutopic (EUE) and normal endometrium (NE). We assessed the expression of miR-17-5p, miR-23a, miR-23b and miR-542-3p, their predicted target genes, steroidogenic acute regulatory protein, aromatase and cyclooxygenase-2, and influence of ovarian steroids on their expression in endometrial stromal (ESC) and glandular epithelial cells (GEC). The results indicated a lower expression of miR-23b and miR-542-3p and higher level of miR-17-5p in paired ECE and EUE as compared with NE. These levels were elevated and inversely correlated with the level of expression of their respective target genes in ECE. The expression of these miRNAs and genes was differentially regulated by 17beta- estradiol, medroxyprogesterone acetate, ICI-182780 and RU-486, or their respective combinations in ESC and GEC. We concluded that altered expression of specific miRNAs in ECE, affecting the stability of their target genes expression, has direct implications in pathogenesis of endometriosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.