Evidence map›Paper›PMID 19087970›Full record

ReviewGenetics2008

Stem cells, their niches and the systemic environment: an aging network.

Daniela Drummond-Barbosa

Open access · bronzeAbstract readReview
In one paragraph

Review in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 125 citations in OpenAlex.

  1. Stem Cell Niche Concept: Search for Current Expert Consensus.International journal of molecular sciences · 2025
    Review
  2. Senescence-Associated Alterations in Matrisome of Mesenchymal Stem Cells.International journal of molecular sciences · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Mitochondrial Control of Stem Cell State and Fate: Lessons FromFrontiers in cell and developmental biology · 2021
    Review
  10. Article
  11. Review
  12. Looking for immortality: Review of phytotherapy for stem cell senescence.Iranian journal of basic medical sciences · 2020
    Review
  13. Article
  14. Biology of theGenetics · 2019
    Review
  15. Bmi1-Progenitor Cell Ablation Impairs the Angiogenic Response to Myocardial Infarction.Arteriosclerosis, thrombosis, and vascular biology · 2018
    Article
  16. Article
  17. Review
  18. Article
  19. Therapeutic roles of telocytes in OVA-induced acute asthma in mice.Journal of cellular and molecular medicine · 2017
    Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Daniela Drummond-BarbosaDepartment of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA. daniela.drummond-barbosa@vanderbilt.edu
Vanderbilt University Medical Center · US

Funding

Nutrient Sensing in Adipocytes and the Control of Oogenesis in DrosophilaR01GM069875 · NIGMS · VANDERBILT UNIVERSITY · PI DRUMMOND-BARBOSA, DANIELA · 2005 to 2020
$5.2M
NIGMS NIH HHS GM 069875NIGMS NIH HHS R01 GM069875
6 · The paper itself

Abstract

Stem cells have a fascinating biology and offer great prospects for therapeutic applications, stimulating intense research on what controls their properties and behavior. Although there have been significant advances in our understanding of how local microenvironments, or niches, control the maintenance and activity of stem cells, it is much less well understood how stem cells sense and respond to variable external, physiological, or tissue environments. This review focuses on the multidirectional interactions among stem cells, niches, tissues, and the systemic environment and on potential ideas for how changes in this network of communication may relate to the aging process.

Indexed as

AgingAnimalsCell CommunicationCellular SenescenceHumansInsulinSignal TransductionStem CellsInsulin

Identifiers

PMID19087970
PMCPMC2600921
OpenAlexW2165716414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.