Evidence map›Paper›PMID 19086827›Full record

ReviewBreastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine2008

Does vitamin D make the world go 'round'?

Carol L Wagner, Sarah N Taylor, Bruce W Hollis

Open access · greenAbstract readReview
In one paragraph

Review in Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. A physiologically based pharmacokinetic model of vitamin D.Journal of applied toxicology : JAT · 2017
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  8. Review
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  12. [Vitamin D supplements in childhood].Atencion primaria · 2012
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Carol L WagnerDepartment of Pediatrics, Pediatric Nutritional Research Center, Darby Children's Research Institute, Medical University of South Carolina, Charleston, South Carolina 29425, USA. wagnercl@musc.edu
Sarah N Taylor
Bruce W Hollis
Medical University of South Carolina · US

Funding

ZINC AND COPPER METABOLISM IN COLLAGEN DISORDERSM01RR001070 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI REVES, JOSEPH G · 1985 to 2009
$16.3M
Establishing the Vitamin D Requirements During LactationR01HD047511 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HOLLIS, BRUCE W · 2006 to 2010
$2.8M
Evaluation of Vitamin D Requirements During PregnancyR01HD043921 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HOLLIS, BRUCE W · 2003 to 2007
$2.6M
NCRR NIH HHS RR01070NICHD NIH HHS 5 R01 HD043921NICHD NIH HHS 5 R01 HD047511
6 · The paper itself

Abstract

Abstract Vitamin D has emerged from obscurity, and its effects on various organ systems throughout the body down to the cellular level are being discovered. What was once thought to be a simple hormone affecting only bone and calcium metabolism has shifted. We no longer see vitamin D as a "vitamin" important only in childhood, but as a complex hormone that is involved not only in calcium homeostasis but also in the integrity of the innate immune system. Vitamin D deficiency is linked to inflammatory and long-latency diseases such as multiple sclerosis, rheumatoid arthritis, tuberculosis, diabetes, and various cancers, to name a few. In this review, we trace how we came to view vitamin D and how that view led to one of the largest epidemics of nutrient deficiency beginning in the late 20(th) century. We then discuss the needs of vitamin D in the context of the breastfeeding mother and her infant and child, why breastfed infants are particularly at risk, and what to do about it.

Indexed as

Immunity, InnateBone and BonesBone Density Conservation AgentsCalciumHumansMilk, HumanRisk FactorsVitamin DVitamin D DeficiencyBone Density Conservation AgentsCalciumVitamin D

Identifiers

PMID19086827
PMCPMC2981372
OpenAlexW1989128180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.