ArticleAmerican journal of obstetrics and gynecology2008
Outcomes of combination treatment of fecal incontinence in women.
Article in American journal of obstetrics and gynecology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03543566 (Antimuscarinic Medication for Urgency Urinary Incontinence in Women With Dual Incontinence), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Antimuscarinic Medication for Urgency Urinary Incontinence in Women With Dual Incontinence (Darifenacin for Treatment of Women With Dual Incontinence)
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Development of an online library of patient-reported outcome measures in gastroenterology: the GI-PRO database.The American journal of gastroenterology · 2014Pooled it
- Characteristics Associated With Clinically Important Treatment Responses in Women Undergoing Nonsurgical Therapy for Fecal Incontinence.The American journal of gastroenterology · 2020Trial
- Pelvic floor muscle exercise and training for coping with urinary incontinence.Journal of exercise rehabilitation · 2021Review
- Epidemiology, pathophysiology, and classification of fecal incontinence: state of the science summary for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) workshop.The American journal of gastroenterology · 2015Article
- A review on functional results of sphincter-saving surgery for rectal cancer: the anterior resection syndrome.Updates in surgery · 2013Review
- Patient-reported outcomes in gastroenterology: clinical and research applications.Journal of neurogastroenterology and motility · 2013Article
- Prevalence and predictive factors of fecal incontinence.Journal of neurogastroenterology and motility · 2012Article
- Anal sphincter repair for fecal incontinence: effect on symptom severity, quality of life, and anal sphincter squeeze pressures.International urogynecology journal · 2011Article
- Symptom improvement in women after fecal incontinence treatments: a multicenter cohort study of the pelvic floor disorders network.Female pelvic medicine & reconstructive surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo describe how women with fecal incontinence (FI) respond to combined pharmacologic therapy and pelvic floor muscle exercises (PFME). STUDY
designValidated questionnaires (Fecal Incontinence Severity Index and Modified Manchester Health Questionnaire) were mailed to 80 women who received combined therapy for FI and had complete baseline assessments. Regression models were constructed to identify predictors of change in questionnaire scores.
resultsResponse rate was 69%. Mean age was 59 +/- 12 years. All women were taught PFME with digital palpation, and 87% of the women received medications. FI severity scores and quality-of-life (QOL) improved from baseline to follow-up (P < .001 and P = .02, respectively). A fair/normal external anal sphincter (EAS) contraction resulted in greater improvements in FI severity (13 points, P = .006) and QOL scores (22 points, P < .001).
conclusionFI severity and QOL improved after combination therapies, and a fair/normal EAS contraction predicted greater improvement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.