ArticleBiomedical microdevices2009
Polymer coating of paramagnetic particulates for in vivo oxygen-sensing applications.
Article in Biomedical microdevices, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Composite spin probes with adjustable oxygen sensitivity for pulse electron paramagnetic resonance imaging.Magnetic resonance in medicine · 2025Article
- Pulse and CW EPR Oximetry Using Oxychip in Gemcitabine-Treated Murine Pancreatic Tumors.Molecular imaging and biology · 2024Article
- Murine Breast Cancer Radiosensitization Using Oxygen Microbubbles and Metformin: Vessels Are the Key.International journal of molecular sciences · 2023Article
- A Dual pH/OMolecules (Basel, Switzerland) · 2022Article
- Characterization of a clinically used charcoal suspension for in vivo EPR oximetry.Magma (New York, N.Y.) · 2019Article
- Skeletal Muscle Oxygenation Measured by EPR Oximetry Using a Highly Sensitive Polymer-Encapsulated Paramagnetic Sensor.Advances in experimental medicine and biology · 2016Article
- Noninvasive monitoring of small intestinal oxygen in a rat model of chronic mesenteric ischemia.Cell biochemistry and biophysics · 2013Article
- A molecular paramagnetic spin-doped biopolymeric oxygen sensor.Biosensors & bioelectronics · 2010Article
- An implantable Teflon chip holding lithium naphthalocyanine microcrystals for secure, safe, and repeated measurements of pO2 in tissues.Biomedical microdevices · 2010Article
- Theory, instrumentation, and applications of electron paramagnetic resonance oximetry.Chemical reviews · 2010Review
- A paramagnetic implant containing lithium naphthalocyanine microcrystals for high-resolution biological oximetry.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2010Article
- Fabrication and physical evaluation of a polymer-encapsulated paramagnetic probe for biomedical oximetry.Biomedical microdevices · 2009Article
- Oxygen sensitivity and biocompatibility of an implantable paramagnetic probe for repeated measurements of tissue oxygenation.Biomedical microdevices · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Crystalline lithium phthalocyanine (LiPc) can be used to sense oxygen. To enhance biocompatibility/stability of LiPc, we encapsulated LiPc in Teflon AF (TAF), cellulose acetate (CA), and polyvinyl acetate (PVAc) (TAF, previously used to encapsulate LiPc, was a comparator). We identified water-miscible solvents that don't dissolve LiPc crystals, but are solvents for the polymers, and encapsulated crystals by solvent evaporation. Oxygen sensitivity of films was characterized in vitro and in vivo. Encapsulation did not change LiPc oximetry properties in vitro at anoxic conditions or varying partial pressures of oxygen (pO2). EPR linewidth of encapsulated particles was linear with pO2, responding to pO2 changes quickly and reproducibly for dynamic measurements. Encapsulated LiPc was unaffected by biological oxidoreductants, stable in vivo for four weeks. Oximetry, stability and biocompatibility properties of LiPc films were comparable, but both CA and PVAc films are cheaper, and easier to fabricate and handle than TAF films, making them superior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.