ArticleInternational journal of legal medicine2009
A GEP-ISFG collaborative study on the optimization of an X-STR decaplex: data on 15 Iberian and Latin American populations.
Article in International journal of legal medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 133 citations in OpenAlex.
- Characterization of a novel unliked 12 X-STR typing assay for forensic purposes in an admixed Rio de Janeiro population sample.Genetics and molecular biology · 2025Article
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- Clinical, cytogenetic, and genomic analyses of an Ecuadorian subject with Klinefelter syndrome, recessive hemophilia A, and 1;19 chromosomal translocation: a case report.Molecular cytogenetics · 2022Article
- Genetic characterization of the highlander Tibetan population from Qinghai-Tibet Plateau revealed by X chromosomal STRs.PloS one · 2022Article
- Study of 17 X-STRs in Native American and Mestizo populations of Central America for forensic and population purposes.International journal of legal medicine · 2021Article
- German population data for 18 X-STRs: a hexaplex PCR adding two clusters of X-STRs to the Argus X-12 set and expanding the German haplotype databases.International journal of legal medicine · 2020Article
- Twenty Years Later: A Comprehensive Review of the X Chromosome Use in Forensic Genetics.Frontiers in genetics · 2020Review
- StatsX v2.0: the interactive graphical software for population statistics on X-STR.International journal of legal medicine · 2019Article
- Curiosities of X chromosomal markers and haplotypes.International journal of legal medicine · 2018Article
- Genetic characterization of an X-STR decaplex system in the State of Mato Grosso, Brazil: distribution, forensic efficiency and population structure.International journal of legal medicine · 2017Article
- Forensic parameters of 19 X-STR polymorphisms in two Chinese populations.International journal of legal medicine · 2017Article
- Potential forensic use of a 33 X-InDel panel in the Argentinean population.International journal of legal medicine · 2017Review
- Development of a 9-locus X-STR multiplex PCR system for genetic analysis of three ethnic populations in China.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015Article
- Brazilian genetic database of chromosome X.Molecular biology reports · 2014Article
- X-STR decaplex study on the population of Czech Republic.International journal of legal medicine · 2014Article
- X-chromosome STR markers data in a Cabo Verde immigrant population of Lisboa.Molecular biology reports · 2014Article
- Impact of a chromosome X STR Decaplex in deficiency paternity cases.Genetics and molecular biology · 2013Article
- Development and validation of a multiplex reaction analyzing eight miniSTRs of the X chromosome for identity and kinship testing with degraded DNA.International journal of legal medicine · 2013Article
- Effect of the parental origin of the X-chromosome on the clinical features, associated complications, the two-year-response to growth hormone (rhGH) and the biochemical profile in patients with turner syndrome.International journal of pediatric endocrinology · 2013Article
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Authors and funding
37 authors at 12 institutions in 6 countries.
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Abstract
In a collaborative work carried out by the Spanish and Portuguese ISFG Working Group (GEP-ISFG), a polymerase chain reaction multiplex was optimized in order to type ten X-chromosome short tandem repeats (STRs) in a single reaction, including: DXS8378, DXS9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7133, GATA172D05, GATA31E08, and DXS7423. Using this X-decaplex, each 17 of the participating laboratories typed a population sample of approximately 200 unrelated individuals (100 males and 100 females). In this work, we report the allele frequencies for the ten X-STRs in 15 samples from Argentina (Buenos Aires, Córdoba, Río Negro, Entre Ríos, and Misiones), Brazil (São Paulo, Rio de Janeiro, Paraná, and Mato Grosso do Sul), Colombia (Antioquia), Costa Rica, Portugal (Northern and Central regions), and Spain (Galicia and Cantabria). Gene diversities were calculated for the ten markers in each population and all values were above 56%. The average diversity per locus varied between 66%, for DXS7133, and 82%, for DXS6809. For this set of STRs, a high discrimination power was obtained in all populations, both in males (> or =1 in 5 x 10(5)) and females (> or =1 in 3 x 10(9)), as well as high mean exclusion chance in father/daughter duos (> or =99.953%) and in father/mother/daughter trios (> or =99.999%). Genetic distance analysis showed no significant differences between northern and central Portugal or between the two Spanish samples from Galicia and Cantabria. Inside Brazil, significant differences were found between Rio de Janeiro and the other three populations, as well as between São Paulo and Paraná. For the five Argentinean samples, significant distances were only observed when comparing Misiones with Entre Ríos and with Río Negro, the only two samples that do not differ significantly from Costa Rica. Antioquia differed from all other samples, except the one from Río Negro.
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