ArticleStructure (London, England : 1993)2008
The 3D structure of villin as an unusual F-Actin crosslinker.
Article in Structure (London, England : 1993), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 42 citations in OpenAlex.
- Genome-Wide Analysis ofCurrent issues in molecular biology · 2024Article
- Genome-Wide Identification and Expression Analysis of thePlants (Basel, Switzerland) · 2023Article
- Cytoskeletal and Cytoskeleton-Associated Proteins: Key Regulators of Cancer Stem Cell Properties.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Structural mechanism for bidirectional actin cross-linking by T-plastin.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli.Cell reports · 2022Article
- Cytoskeletal Remodeling in Cancer.Biology · 2020Review
- F-actin-bundling sites are conserved in proteins with villin-type headpiece domains.Molecular biology of the cell · 2020Article
- An Auxin Transport Inhibitor Targets Villin-Mediated Actin Dynamics to Regulate Polar Auxin Transport.Plant physiology · 2019Article
- Identification of interfaces involved in weak interactions with application to F-actin-aldolase rafts.Journal of structural biology · 2018Article
- My various thoughts on actin.Biophysics and physicobiology · 2018Review
- Generation of intestinal surface: an absorbing tale.Development (Cambridge, England) · 2016Review
- Gelsolin-Like Domain 3 Plays Vital Roles in Regulating the Activities of the Lily Villin/Gelsolin/Fragmin Superfamily.PloS one · 2015Article
- Medaka villin 1-like protein (VILL) is associated with the formation of microvilli induced by decreasing salinities in the absorptive ionocytes.Frontiers in zoology · 2014Article
- Biophysics of actin filament severing by cofilin.FEBS letters · 2013Review
- The allosteric mechanism induced by protein kinase A (PKA) phosphorylation of dematin (band 4.9).The Journal of biological chemistry · 2013Article
- Electron tomography of paracrystalline 2D arrays.Methods in molecular biology (Clifton, N.J.) · 2013Article
- Arabidopsis VILLIN2 and VILLIN3 are required for the generation of thick actin filament bundles and for directional organ growth.Plant physiology · 2012Article
- Putting structure into context: fitting of atomic models into electron microscopic and electron tomographic reconstructions.Current opinion in cell biology · 2012Review
- Competition between intradomain and interdomain interactions: a buried salt bridge is essential for villin headpiece folding and actin binding.Biochemistry · 2011Article
- Arabidopsis VILLIN1 and VILLIN3 have overlapping and distinct activities in actin bundle formation and turnover.The Plant cell · 2010Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Villin is an F-actin nucleating, crosslinking, severing, and capping protein within the gelsolin superfamily. We have used electron tomography of 2D arrays of villin-crosslinked F-actin to generate 3D images revealing villin's crosslinking structure. In these polar arrays, neighboring filaments are spaced 125.9 +/- 7.1 A apart, offset axially by 17 A, with one villin crosslink per actin crossover. More than 6500 subvolumes containing a single villin crosslink and the neighboring actin filaments were aligned and classified to produce 3D subvolume averages. Placement of a complete villin homology model into the average density reveals that full-length villin binds to different sites on F-actin from those used by other actin-binding proteins and villin's close homolog gelsolin.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.