ArticlePhysica A2006
Transport of a 1D viscoelastic actin-myosin strip of gel as a model of a crawling cell.
Article in Physica A, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- A geometric-surface PDE model for cell-nucleus translocation through confinement.PLoS computational biology · 2026Article
- Nonlinear Stability in a Free Boundary Model of Active Locomotion.Archive for rational mechanics and analysis · 2026Article
- Modeling actin-microtubule crosstalk in migrating cells.Biophysical journal · 2025Article
- Article
- On a poroviscoelastic model for cell crawling.Journal of mathematical biology · 2015Article
- A simple force-motion relation for migrating cells revealed by multipole analysis of traction stress.Biophysical journal · 2014Article
- A viscoelastic model of blood capillary extension and regression: derivation, analysis, and simulation.Journal of mathematical biology · 2014Article
- Probing cellular mechanoadaptation using cell-substrate de-adhesion dynamics: experiments and model.PloS one · 2014Article
- Modeling of adhesion, protrusion, and contraction coordination for cell migration simulations.Journal of mathematical biology · 2014Article
- Migration of cells in a social context.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Emergent complexity of the cytoskeleton: from single filaments to tissue.Advances in physics · 2013Review
- Mathematical modeling of the impact of actin and keratin filaments on keratinocyte cell spreading.Biophysical journal · 2012Article
- Modelling cell motility and chemotaxis with evolving surface finite elements.Journal of the Royal Society, Interface · 2012Article
- Continuum modeling and numerical simulation of cell motility.Journal of mathematical biology · 2012Article
- Coupling actin flow, adhesion, and morphology in a computational cell motility model.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- A comparison of computational models for eukaryotic cell shape and motility.PLoS computational biology · 2012Review
- Mechanisms of Cell Propulsion by Active Stresses.New journal of physics · 2011Article
- Nanoscale tissue engineering: spatial control over cell-materials interactions.Nanotechnology · 2011Review
- A POROELASTIC MODEL FOR CELL CRAWLING INCLUDING MECHANICAL COUPLING BETWEEN CYTOSKELETAL CONTRACTION AND ACTIN POLYMERIZATION.Journal of mechanics of materials and structures · 2011Article
- Computational model for cell morphodynamics.Physical review letters · 2010Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Cell crawling is an important biological phenomenon because it underlies coordinated cell movement in morphogenesis, cancer and wound healing. This phenomenon is based on protrusion at the cell's leading edge, retraction at the rear, contraction and graded adhesion powered by the dynamics of actin and myosin protein networks. A few one-dimensional models successfully explain an anteroposterior organization of the motile cell, but don't sufficiently explore the viscoelastic nature of the actin-myosin gel. We develop and numerically solve a model of a treadmilling strip of viscoelastic actin-myosin gel. The results show that the strip translocates steadily as a traveling pulse, without changing length, and that protein densities, velocities and stresses become stationary. The simulations closely match the observed forces, movements and protein distributions in the living cell.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.