Evidence map›Paper›PMID 19079351›Full record

ReviewNature reviews. Microbiology2009

Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium.

Klas Flärdh, Mark J Buttner

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 337 papers.

0numbers the graph read from it
0cells of the map it votes in
337citing papers in PubMed
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

337 citing papers in PubMed, 670 citations in OpenAlex.

  1. Novel insights on carbon source influence on azomycin production by Streptomyces eurocidicus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  17. Lon protease reprograms cellular physiology ofFrontiers in microbiology · 2026
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277 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Klas FlärdhDepartment of Cell and Organism Biology, Lund University, Lund, Sweden. mark.buttner@bbsrc.ac.uk
Mark J Buttner
John Innes Centre · GBLund University · SE

Funding

Biotechnology and Biological Sciences Research Council BBS/E/J/00000015
6 · The paper itself

Abstract

During the life cycle of the filamentous bacteria Streptomyces, morphological differentiation is closely integrated with fundamental growth and cell-cycle processes, as well as with truly complex multicellular behaviour that involves hormone-like extracellular signalling and coordination with an extraordinarily diverse secondary metabolism. Not only are the bacterial cytoskeleton and the machineries for cell-wall assembly, cell division and chromosome segregation reorganized during sporulation, but the developmental programme of these fascinating organisms also has many unusual elements, including the formation of a sporulating aerial mycelium and the production of a surfactant peptide and a hydrophobic sheath that allow cells to escape from the surface tension of the growth medium.

Indexed as

MorphogenesisStreptomyces

Identifiers

PMID19079351
OpenAlexW2086506761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.