ArticleEukaryotic cell2009
The white cell response to pheromone is a general characteristic of Candida albicans strains.
Article in Eukaryotic cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Fungal biofilm formation and quorum sensing: Regulatory mechanisms and control strategies.World journal of microbiology & biotechnology · 2026Review
- Unraveling HowJournal of fungi (Basel, Switzerland) · 2020Review
- Plasticity of Candida albicans Biofilms.Microbiology and molecular biology reviews : MMBR · 2016Review
- Impact of environmental conditions on the form and function of Candida albicans biofilms.Eukaryotic cell · 2013Article
- Candida albicans forms a specialized "sexual" as well as "pathogenic" biofilm.Eukaryotic cell · 2013Article
- Identification of genes upregulated by the transcription factor Bcr1 that are involved in impermeability, impenetrability, and drug resistance of Candida albicans a/α biofilms.Eukaryotic cell · 2013Article
- Review
- Alternative mating type configurations (a/α versus a/a or α/α) of Candida albicans result in alternative biofilms regulated by different pathways.PLoS biology · 2011Article
- Self-induction of a/a or alpha/alpha biofilms in Candida albicans is a pheromone-based paracrine system requiring switching.Eukaryotic cell · 2011Article
- Evolution of mating within the Candida parapsilosis species group.Eukaryotic cell · 2011Article
- Article
- Sexual reproduction in the Candida clade: cryptic cycles, diverse mechanisms, and alternative functions.Cellular and molecular life sciences : CMLS · 2010Review
- The evolution of sex: a perspective from the fungal kingdom.Microbiology and molecular biology reviews : MMBR · 2010Review
- Tec1 mediates the pheromone response of the white phenotype of Candida albicans: insights into the evolution of new signal transduction pathways.PLoS biology · 2010Article
- Fungal sex and pathogenesis.Clinical microbiology reviews · 2010Review
- Genes selectively up-regulated by pheromone in white cells are involved in biofilm formation in Candida albicans.PLoS pathogens · 2009Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
For Candida albicans, evidence has suggested that the mating pheromones activate not only the mating response in mating-competent opaque cells but also a unique response in mating-incompetent white cells that includes increased cohesion and adhesion, enhanced biofilm formation, and expression of select mating-related and white cell-specific genes. On the basis of a recent microarray analysis comparing changes in the global expression patterns of white cells in two strains in response to alpha-pheromone, however, skepticism concerning the validity and generality of the white cell response has been voiced. Here, we present evidence that the response occurs in all tested media (Lee's, RPMI, SpiderM, yeast extract-peptone-dextrose, and a synthetic medium) and in all of the 27 tested strains, including a/a and alpha/alpha strains, derivatives of the common laboratory strain SC5314, and representatives from all of the five major clades. The white cell response to pheromone is therefore a general characteristic of MTL-homozygous strains of C. albicans.
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