Evidence map›Paper›PMID 19072643›Full record

ReviewPharmacogenomics2008

Epigenetics and obesity.

Reinhard Stöger

Abstract readReview
In one paragraph

Review in Pharmacogenomics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Role of long non-coding RNAs in adipogenesis: State of the art and implications in obesity and obesity-associated diseases.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Review
  7. Metabolic and Energy Imbalance in Dysglycemia-Based Chronic Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Multiple conditions: exploring literature from the consumer perspective in Australia.Health expectations : an international journal of public participation in health care and health policy · 2015
    Review
  15. Genetic & epigenetic approach to human obesity.The Indian journal of medical research · 2014
    Review
  16. Article
  17. Impact of diabetes on cardiovascular disease: an update.International journal of hypertension · 2013 · on this map
    Article
  18. Article
  19. Article
  20. Microvesicles/exosomes as potential novel biomarkers of metabolic diseases.Diabetes, metabolic syndrome and obesity : targets and therapy · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Reinhard StögerDepartment of Biology, University of Washington, 156 Kincaid Hall, Box 351800, Seattle, WA, 98195-1800, USA. stoeger@u.washington.edu

Funding

Shotgun Hairpin-Bisulfite PCR Reveals Genome Methylation and Sequence VariationR01GM077464 · NIGMS · UNIVERSITY OF WASHINGTON · PI LAIRD, CHARLES D · 2006 to 2008
$773k
NIGMS NIH HHS GM077464NIGMS NIH HHS R01 GM077464
6 · The paper itself

Abstract

Common DNA sequence variants inadequately explain variability in fat mass among individuals. Abnormal body weights are characteristic of specific imprinted-gene disorders. However, the relevance of imprinted genes to our understanding of obesity among the general population is uncertain. Hitherto unidentified imprinted genes and epigenetic mosaicism are two of the challenges for this emerging field of epigenetics. Subtle epigenetic differences in imprinted genes and gene networks are likely to be present among cells, tissues and individuals. In order to advance obesity research it will be necessary to use genome-wide, next-generation sequencing approaches that allow the detection of such epigenetic differences.

Indexed as

Epigenesis, GeneticAnimalsEnergy MetabolismGenomic ImprintingHumansObesity

Identifiers

PMID19072643
PMCPMC2652025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.