Evidence map›Paper›PMID 19072463›Full record

ReviewWomen's health (London, England)2008

New treatments for irritable bowel syndrome in women.

Mopelola A Adeyemo, Lin Chang

Abstract readReview
In one paragraph

Review in Women's health (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Sex and disease-related alterations of anterior insula functional connectivity in chronic abdominal pain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
  3. Frequency of abnormal fecal biomarkers in irritable bowel syndrome.Global advances in health and medicine · 2014
    Article
  4. Article
  5. Article
  6. Diagnosis and management of IBS.Nature reviews. Gastroenterology & hepatology · 2010
    Review
  7. To match or not to match in epidemiological studies--same outcome but less power.International journal of environmental research and public health · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mopelola A AdeyemoCenter for Neurobiology of Stress, Division of Digestive Diseases, David Geffen School of Medicine at UCLA, 11301 Wilshire Blvd, Building 115, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA. madeyemo@mednet.ucla.edu
Lin Chang

Funding

Women's Health and Functional Visceral Disorders CenterP50DK064539 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYER, EMERAN A · 2002 to 2017
$17.5M
NEUROENDOCRINE ALTERATIONS IN FIBROMYALGIA AND IBSR01AR046122 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHANG, LIN · 1999 to 2010
$2.4M
NIAMS NIH HHS R01 AR046122NIDDK NIH HHS P50 DK064539
6 · The paper itself

Abstract

The estimated prevalence of irritable bowel syndrome (IBS) in Western countries is 7-15%, with a female:male ratio of 2-2.5:1 in IBS patients who seek healthcare services; however, the female predominance is lower in the general population. IBS has a significant impact on health-related quality of life and is associated with a significant healthcare and economic burden. Management of IBS is comprised of general measures and pharmacologic and nonpharmacologic treatment. However, there are ongoing efforts to find more effective therapeutic approaches. As advancements in the understanding of the pathophysiology of IBS continue to grow, new and effective treatments with novel mechanisms of action that have the potential to improve relief of IBS symptoms over current treatments are likely to be developed. This article provides an overview of current and emerging therapies for IBS and also highlights sex and gender differences in clinical trials and treatment response.

Indexed as

BenzofuransComplementary TherapiesDiet TherapyFemaleFibrinolytic AgentsGastrointestinal AgentsHumansIrritable Bowel SyndromeMaleRandomized Controlled Trials as TopicSex DistributionBenzofuransFibrinolytic AgentsGastrointestinal Agentsprucalopride

Identifiers

PMID19072463
PMCPMC2652519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.