Evidence map›Paper›PMID 19072304›Full record

ArticleNano letters2009

The impact of conformational fluctuations on self-assembly: cooperative aggregation of archaeal chaperonin proteins.

Stephen Whitelam, Carl Rogers, Andrea Pasqua, Chad Paavola, Jonathan Trent, Phillip L Geissler

Abstract read
In one paragraph

Article in Nano letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Limits of economy and fidelity for programmable assembly of size-controlled triply periodic polyhedra.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Article
  5. Bottom-up Coarse-Graining: Principles and Perspectives.Journal of chemical theory and computation · 2022
    Review
  6. Temperature protocols to guide selective self-assembly of competing structures.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
  8. Programming colloidal bonding using DNA strand-displacement circuitry.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  9. Nonequilibrium associative retrieval of multiple stored self-assembly targets.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  10. Mechanisms of virus assembly.Annual review of physical chemistry · 2015
    Review
  11. Pathways for virus assembly around nucleic acids.Journal of molecular biology · 2014
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Modeling Viral Capsid Assembly.Advances in chemical physics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stephen WhitelamSystems Biology Centre, University of Warwick, Coventry CV4 7AL, U.K., Biophysics Graduate Group, University of California at Berkeley, Berkeley, California 94720, USA.
Carl Rogers
Andrea Pasqua
Chad Paavola
Jonathan Trent
Phillip L Geissler

Funding

MOLECULAR BIOPHYSICS TRAINING GRANTT32GM008295 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HURLEY, JAMES H, WEMMER, DAVID E · 1989 to 2022
$8.1M
NIGMS NIH HHS T32 GM008295NIGMS NIH HHS T32GM08295
6 · The paper itself

Abstract

Protein complexes called rosettasomes self-assemble in solution to form large-scale filamentous and planar structures. The relative abundance of these aggregates varies abruptly with environmental conditions and sample composition. Our simulations of a model of patchy nanoparticles can reproduce this sharp crossover, but only if particles are allowed to switch between two internal states favoring different geometries of local binding. These results demonstrate how local conformational adaptivity can fundamentally influence the cooperativity of pattern-forming dynamics.

Indexed as

Models, ChemicalModels, MolecularChaperoninsComputer SimulationDimerizationMultiprotein ComplexesNanostructuresParticle SizeProtein ConformationSulfolobusChaperoninsMultiprotein Complexes

Identifiers

PMID19072304
PMCPMC2670443

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.