ReviewCurrent opinion in pharmacology2009
Possible novel targets for therapeutic angiogenesis.
Review in Current opinion in pharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Article
- Notch-1 inhibition reduces proliferation and promotes osteogenic differentiation of bone marrow mesenchymal stem cells.Experimental and therapeutic medicine · 2019Article
- Role of Hedgehog Signaling in Vasculature Development, Differentiation, and Maintenance.International journal of molecular sciences · 2019Review
- Antisense Oligonucleotides Targeting Angiogenic Factors as Potential Cancer Therapeutics.Molecular therapy. Nucleic acids · 2019Review
- Platelet-Rich Plasma with Endothelial Progenitor Cells Accelerates Diabetic Wound Healing in Rats by Upregulating the Notch1 Signaling Pathway.Journal of diabetes research · 2019Article
- Coculture of endothelial progenitor cells and mesenchymal stem cells enhanced their proliferation and angiogenesis through PDGF and Notch signaling.FEBS open bio · 2017Article
- C1q/Tumor Necrosis Factor-Related Protein-3 Attenuates Brain Injury after Intracerebral Hemorrhage via AMPK-Dependent Pathway in Rat.Frontiers in cellular neuroscience · 2016Article
- The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.PLoS pathogens · 2015Article
- The involvement of Notch signaling in melanoma vasculogenic mimicry.Clinical and experimental medicine · 2013Article
- Suppression of retinal neovascularization by lentivirus-mediated netrin-1 small hairpin RNA.Ophthalmic research · 2012Article
- Intravitreous high expression level of netrin-1 in patients with proliferative diabetic retinopathy.Eye science · 2011Article
- Reduced expression of netrin-1 is associated with fetal growth restriction.Molecular and cellular biochemistry · 2011Article
- Role of axonal guidance factor netrin-1 in human placental vascular growth.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2011Article
- Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis.The Journal of biological chemistry · 2011Article
- What role for angiogenesis in childhood acute lymphoblastic leukaemia?Advances in hematology · 2011Article
- Neurotrophin-3 is a novel angiogenic factor capable of therapeutic neovascularization in a mouse model of limb ischemia.Arteriosclerosis, thrombosis, and vascular biology · 2010Article
- New discovery of Netrin-1 in cardioprotection.Journal of molecular and cellular cardiology · 2010Article
- Nerve growth factor-induced protection of brain capillary endothelial cells exposed to oxygen-glucose deprivation involves attenuation of Erk phosphorylation.Journal of molecular neuroscience : MN · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increasing number of studies about the molecular basis of angiogenesis are rapidly disclosing novel signal pathways involved in the blood vessel formation process. This review will focus on bone morphogenic proteins, Hedgehog, Notch, ephrins, neuropilins, neurotrophins and netrins. These recently discovered angiogenesis mediators are involved in vascular development during embryogenesis and, interestingly, they are shared between the nervous and vascular systems. They represent new potential targets in the vasculature and suggest novel therapeutic opportunities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.