ArticleCell2008
No association between CALHM1 and Alzheimer's disease risk.
Article in Cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Genetic association of CALHM1 rs2986017 polymorphism with risk of Alzheimer's disease: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2016Pooled it
- The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study.Journal of Alzheimer's disease : JAD · 2010Pooled it
- Role of Calcium Homeostasis in Alzheimer's Disease.Neuropsychiatric disease and treatment · 2022Review
- Calcium homeostasis modulator (CALHM) ion channels.Pflugers Archiv : European journal of physiology · 2016Review
- Genetic Factors Affecting Late-Onset Alzheimer's Disease Susceptibility.Neuromolecular medicine · 2016Article
- Do Copy Number Changes in CACNA2D2, CACNA2D3, and CACNA1D Constitute a Predisposing Risk Factor for Alzheimer's Disease?Frontiers in genetics · 2016Article
- Article
- Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.Neurobiology of aging · 2015Article
- Rare autosomal copy number variations in early-onset familial Alzheimer's disease.Molecular psychiatry · 2014Article
- CLHM-1 is a functionally conserved and conditionally toxic Ca2+-permeable ion channel in Caenorhabditis elegans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis.PloS one · 2013Article
- Stabilizers of neuronal and mitochondrial calcium cycling as a strategy for developing a medicine for Alzheimer's disease.ACS chemical neuroscience · 2012Review
- Amyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS development.PloS one · 2012Article
- Endoplasmic reticulum Ca(2+) handling in excitable cells in health and disease.Pharmacological reviews · 2011Review
- Identification of a polyI:C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation.The Journal of experimental medicine · 2010Article
- Association of CALHM1 Gene Polymorphism with Late Onset Alzheimer's Disease in Iranian Population.Avicenna journal of medical biotechnology · 2010Article
- Calcium signaling and neurodegeneration.Acta naturae · 2010Article
- The dysregulation of intracellular calcium in Alzheimer disease.Cell calcium · 2010Review
- CALHM1 P86L polymorphism does not alter amyloid-beta or tau in cerebrospinal fluid.Neuroscience letters · 2010Article
- Validating predicted biological effects of Alzheimer's disease associated SNPs using CSF biomarker levels.Journal of Alzheimer's disease : JAD · 2010Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.