Evidence map›Paper›PMID 19068160›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2008

Trends and inequities in beta-blocker prescribing for heart failure.

Sunil M Shah, Iain M Carey, Stephen DeWilde, Nicky Richards, Derek G Cook

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  11. Review
  12. β blockers for heart failure.BMJ (Clinical research ed.) · 2016
    Article
  13. Article
  14. Cardiac arrest: the changing incidence of ventricular fibrillation.Current treatment options in cardiovascular medicine · 2015
    Article
  15. Article
  16. Socioeconomic status influences the likelihood but not the outcome of liver resection for colorectal liver metastasis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015
    Article
  17. Article
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  20. Home blood pressure monitoring.The British journal of general practice : the journal of the Royal College of General Practitioners · 2009
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sunil M ShahDivision of Community Health Sciences, St George's, University of London, Cranmer Terrace. sushah@sgul.ac.uk
Iain M Carey
Stephen DeWilde
Nicky Richards
Derek G Cook
St George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTreatment with specific beta-blockers reduces mortality and hospitalisation in heart failure.

aimTo describe trends and inequities in beta-blocker prescribing for heart failure. DESIGN OF STUDY: Repeated cross-sectional analysis of a nationally representative primary care database (DIN-LINK).

settingA total of 152 UK general practices.

methodPrescribing of beta-blockers between 2000 and 2005 was examined among a yearly average of 7294 patients aged>or=50 years who had actively managed heart failure - defined as a recorded diagnosis of heart failure and two prescriptions of an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker during the calendar year. The main outcome was the prescription of a guideline-recommended beta-blocker (bisoprolol, carvedilol, metoprolol, or nebivolol) in the year. Determinants of beta-blocker prescribing were analysed using logistic regression.

resultsBetween 2000 and 2005, age-adjusted use of recommended beta-blockers rose from 6.1% to 27.0% in men, and from 4.2% to 21.5% in women. In 2005, younger patients were more likely to be treated; the fully adjusted odds ratio was 4.83 (95% confidence interval=3.78 to 6.17) for patients aged 60-64 years compared with those aged 85 years. Women and patients living in areas of socioeconomic deprivation were less likely to be treated. In 2005, in addition to treatment with guideline-recommended beta-blockers, a further 11.7% of men and 12.5% of women were prescribed other beta-blockers.

conclusionRecommended beta-blocker use has risen in the UK but remains low and inequitable, with many patients still treated with beta-blockers that are not recommended in guidelines. This suggests further improvements in prescribing are still possible.

Indexed as

Adrenergic beta-AntagonistsAgedAged, 80 and overCross-Sectional StudiesFamily PracticeFemaleGuideline AdherenceHeart FailureHumansMaleMiddle AgedPractice Guidelines as TopicProfessional PracticeRegression AnalysisAdrenergic beta-Antagonists

Identifiers

PMID19068160
PMCPMC2593536
OpenAlexW2084133661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.