ArticlePLoS medicine2008
Bias, spin, and misreporting: time for full access to trial protocols and results.
Article in PLoS medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Time to publication for results of clinical trials.The Cochrane database of systematic reviews · 2024Pooled it
- Overinterpretation and misreporting of prognostic factor studies in oncology: a systematic review.British journal of cancer · 2018Pooled it
- A systematic review of comparisons between protocols or registrations and full reports in primary biomedical research.BMC medical research methodology · 2018Pooled it
- Comparative effect sizes in randomised trials from less developed and more developed countries: meta-epidemiological assessment.BMJ (Clinical research ed.) · 2013Pooled it
- Treatment success in cancer: industry compared to publicly sponsored randomized controlled trials.PloS one · 2013Pooled it
- Deficiencies in the transfer and availability of clinical trials evidence: a review of existing systems and standards.BMC medical informatics and decision making · 2012Pooled it
- Pooled it
- Novel methods to deal with publication biases: secondary analysis of antidepressant trials in the FDA trial registry database and related journal publications.BMJ (Clinical research ed.) · 2009Pooled it
- A Randomized Crossover Trial Evaluating Continuous Positive Airway Pressure Versus Mandibular Advancement Device on Health Outcomes in Veterans With Posttraumatic Stress Disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017Trial
- Trial
- Trial
- SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials.BMJ (Clinical research ed.) · 2025Article
- Barriers to publishing early phase clinical trials: the oncologists' perspective.The oncologist · 2025Article
- When to believe a subgroup analysis: revisiting the 11 criteria.Eye (London, England) · 2022Article
- Transparent, Open, and Reproducible Prevention Science.Prevention science : the official journal of the Society for Prevention Research · 2022Article
- Analysis of 567,758 randomized controlled trials published over 30 years reveals trends in phrases used to discuss results that do not reach statistical significance.PLoS biology · 2022Article
- Ensuring the quality and specificity of preregistrations.PLoS biology · 2020Article
- Methodological Biases in CBT Trial-Commentary: Modular Cognitive-Behavioral Therapy for Affective Symptoms in Young Individuals at Ultra-High Risk of First Episode of Psychosis: Randomized Controlled Trial.Frontiers in psychiatry · 2020Article
- Characteristic Analysis of Complementary and Alternative Medicine in Randomized Controlled Trials of Oncology: A Comparison of Published Studies.Integrative cancer therapies · 2018Article
- A quality analysis of clinical anaesthesia study protocols from the Chinese clinical trials registry according to the SPIRIT statement.Oncotarget · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.