Trial reportPLoS medicine2008
The long-term effects of a peer-led sex education programme (RIPPLE): a cluster randomised trial in schools in England.
Trial report in PLoS medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 9 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- School-based peer education interventions to improve health: a global systematic review of effectiveness.BMC public health · 2022Pooled it
- A systematic review of the evidence on peer education programmes for promoting the sexual and reproductive health of young people in India.Sexual and reproductive health matters · 2020Pooled it
- School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents.The Cochrane database of systematic reviews · 2016Pooled it
- School-based interventions for improving contraceptive use in adolescents.The Cochrane database of systematic reviews · 2016Pooled it
- Brief educational strategies for improving contraception use in young people.The Cochrane database of systematic reviews · 2016Pooled it
- Interventions for preventing unintended pregnancies among adolescents.The Cochrane database of systematic reviews · 2016Pooled it
- Behavioral interventions for improving condom use for dual protection.The Cochrane database of systematic reviews · 2013Pooled it
- Interventions for encouraging sexual behaviours intended to prevent cervical cancer.The Cochrane database of systematic reviews · 2011Pooled it
- [Effectiveness of educational interventions for the prevention of pregnancy in adolescents].Atencion primariaPooled it
- Effects of a whole-school relationships and sexual health intervention on non-competent sexual debut: cluster-randomised trial.Journal of epidemiology and community health · 2026Trial
- Trial
- Trial
- Effects of an Interactive School-Based Program for Preventing Adolescent Sexual Harassment: A Cluster-Randomized Controlled Evaluation Study.Journal of youth and adolescence · 2016Trial
- Trial
- Evaluation of a peer-led asthma self-management program and benefits of the program for adolescent peer leaders.Respiratory care · 2012Trial
- Long-term biological and behavioural impact of an adolescent sexual health intervention in Tanzania: follow-up survey of the community-based MEMA kwa Vijana Trial.PLoS medicine · 2010Trial
- The impact of implementation of sex education in schools, and its applicability in Kazakhstan.Frontiers in global women's health · 2026Review
- Cost-benefit analysis of adolescent HIV/STI prevention and comprehensive sexuality education interventions in Cambodia: a modelling study.BMJ public health · 2026Article
- Systematic review: risk sexual behavior, sexually transmitted infections, and adolescent pregnancy prevention interventions.Journal of public health in Africa · 2023Article
- Interventions to prevent unintended pregnancies among adolescents: a rapid overview of systematic reviews.Systematic reviews · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPeer-led sex education is widely believed to be an effective approach to reducing unsafe sex among young people, but reliable evidence from long-term studies is lacking. To assess the effectiveness of one form of school-based peer-led sex education in reducing unintended teenage pregnancy, we did a cluster (school) randomised trial with 7 y of follow-up. METHODS AND
findingsTwenty-seven representative schools in England, with over 9,000 pupils aged 13-14 y at baseline, took part in the trial. Schools were randomised to either peer-led sex education (intervention) or to continue their usual teacher-led sex education (control). Peer educators, aged 16-17 y, were trained to deliver three 1-h classroom sessions of sex education to 13- to 14-y-old pupils from the same schools. The sessions used participatory learning methods designed to improve the younger pupils' skills in sexual communication and condom use and their knowledge about pregnancy, sexually transmitted infections (STIs), contraception, and local sexual health services. Main outcome measures were abortion and live births by age 20 y, determined by anonymised linkage of girls to routine (statutory) data. Assessment of these outcomes was blind to sex education allocation. The proportion of girls who had one or more abortions before age 20 y was the same in each arm (intervention, 5.0% [95% confidence interval (CI) 4.0%-6.3%]; control, 5.0% [95% CI 4.0%-6.4%]). The odds ratio (OR) adjusted for randomisation strata was 1.07 (95% CI 0.80-1.42, p = 0.64, intervention versus control). The proportion of girls with one or more live births by 20.5 y was 7.5% (95% CI 5.9%-9.6%) in the intervention arm and 10.6% (95% CI 6.8%-16.1%) in the control arm, adjusted OR 0.77 (0.51-1.15). Fewer girls in the peer-led arm self-reported a pregnancy by age 18 y (7.2% intervention versus 11.2% control, adjusted OR 0.62 [95% CI 0.42-0.91], weighted for non-response; response rate 61% intervention, 45% control). There were no significant differences for girls or boys in self-reported unprotected first sex, regretted or pressured sex, quality of current sexual relationship, diagnosed sexually transmitted diseases, or ability to identify local sexual health services.
conclusionCompared with conventional school sex education at age 13-14 y, this form of peer-led sex education was not associated with change in teenage abortions, but may have led to fewer teenage births and was popular with pupils. It merits consideration within broader teenage pregnancy prevention strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.