Randomized trials of antioxidant supplementation for cancer prevention: first bias, now chance--next, cause.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed.

1. A comparison of a ketogenic diet with a LowGI/nutrigenetic diet over 6 months for weight loss and 18-month follow-up.BMC nutrition · 2020
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2. Vitamins, metabolomics, and prostate cancer.World journal of urology · 2017
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3. Effect of Saw Palmetto Supplements on Androgen-Sensitive LNCaP Human Prostate Cancer Cell Number and Syrian Hamster Flank Organ Growth.Evidence-based complementary and alternative medicine : eCAM · 2016
   Article
4. Selenium for the prevention of cutaneous melanoma.Nutrients · 2013
   Article
5. The influence of micronutrients in cell culture: a reflection on viability and genomic stability.BioMed research international · 2013
   Review
6. Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control study.PloS one · 2012
   Article
7. Wolfberry Water Soluble Phytochemicals Down-Regulate ER Stress Biomarkers and Modulate Multiple Signaling Pathways Leading To Inhibition of Proliferation and Induction of Apoptosis in Jurkat Cells.Journal of nutrition & food sciences · 2011
   Article
8. Vitamins C and E: beneficial effects from a mechanistic perspective.Free radical biology & medicine · 2011
   Review
9. Genetic variation in myeloperoxidase modifies the association of serum α-tocopherol with aggressive prostate cancer among current smokers.The Journal of nutrition · 2011
   Article
10. Calorie restriction and prevention of age-associated chronic disease.FEBS letters · 2011
    Review
11. Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors.PloS one · 2010
    Article
12. Mitochondrial respiration protects against oxygen-associated DNA damage.Nature communications · 2010
    Article
13. Nutraceuticals and prostate cancer prevention: a current review.Nature reviews. Urology · 2010
    Review
14. Selenium in oncology: from chemistry to clinics.Molecules (Basel, Switzerland) · 2009
    Review

Corrections and comments

• Commented on by
  Antioxidant supplementation and cancer prevention.2009
• Commented on by
  Antioxidant supplementation and cancer prevention.2009
• Comment on
  Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial.2009
• Comment on
  Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).2009

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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