ReviewNature reviews. Genetics2009
Genotype-phenotype databases: challenges and solutions for the post-genomic era.
Review in Nature reviews. Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A blockchain-based framework to support pharmacogenetic data sharing.The pharmacogenomics journal · 2022Pooled it
- FAIR Header Reference genome: a TRUSTworthy standard.Briefings in bioinformatics · 2024Article
- Non-Local Parallel Processing and Database Settlement Using Multiple Teleportation Followed by Grover Post-Selection.Entropy (Basel, Switzerland) · 2023Article
- Computational approaches for predicting variant impact: An overview from resources, principles to applications.Frontiers in genetics · 2022Review
- A Blockchain-Based Dynamic Consent Architecture to Support Clinical Genomic Data Sharing (ConsentChain): Proof-of-Concept Study.JMIR medical informatics · 2021Article
- Development of a four-gene prognostic model for pancreatic cancer based on transcriptome dysregulation.Aging · 2020Article
- Learning Lessons on Reproducibility and Replicability in Large Scale Genome-Wide Association Studies.Harvard data science review · 2020Article
- Single Nucleotide Polymorphism Genotyping in Single-Molecule Electronic Circuits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2017Article
- Article
- Publisher’s Note:Abstraction for data integration:Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction.Computational biology and chemistry · 2015Article
- Deciphering next-generation pharmacogenomics: an information technology perspective.Open biology · 2014Article
- Annotating DNA variants is the next major goal for human genetics.American journal of human genetics · 2014Article
- Article
- Neurocarta: aggregating and sharing disease-gene relations for the neurosciences.BMC genomics · 2013Article
- Toward knowledge support for analysis and interpretation of complex traits.Genome biology · 2013Review
- DcGO: database of domain-centric ontologies on functions, phenotypes, diseases and more.Nucleic acids research · 2013Article
- From ontology to semantic similarity: calculation of ontology-based semantic similarity.TheScientificWorldJournal · 2013Review
- Managing sensitive phenotypic data and biomaterial in large-scale collaborative psychiatric genetic research projects: practical considerations.Molecular psychiatry · 2012Article
- Computational tools for comparative phenomics: the role and promise of ontologies.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Review
- Using PhenX measures to identify opportunities for cross-study analysis.Human mutation · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The flow of research data concerning the genetic basis of health and disease is rapidly increasing in speed and complexity. In response, many projects are seeking to ensure that there are appropriate informatics tools, systems and databases available to manage and exploit this flood of information. Previous solutions, such as central databases, journal-based publication and manually intensive data curation, are now being enhanced with new systems for federated databases, database publication, and more automated management of data flows and quality control. Along with emerging technologies that enhance connectivity and data retrieval, these advances should help to create a powerful knowledge environment for genotype-phenotype information.
Indexed as
Identifiers
19065136What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.