Evidence map›Paper›PMID 19064894›Full record

ArticleAntimicrobial agents and chemotherapy2009

Molecular analysis of the sequences surrounding blaOXA-45 reveals acquisition of this gene by Pseudomonas aeruginosa via a novel ISCR element, ISCR5.

Hongyang Li, Timothy R Walsh, Mark A Toleman

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. OXA β-lactamases.Clinical microbiology reviews · 2014
    Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hongyang LiDepartment of Medical Microbiology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.
Timothy R Walsh
Mark A Toleman

Funding

Wellcome TrustWellcome Trust WT084627MF
6 · The paper itself

Abstract

The bla(OXA-45) gene of Pseudomonas aeruginosa 07-406 is driven by a promoter found within a truncated ISPme1 insertion sequence. The gene is located between nonidentical repeats of a new ISCR element, ISCR5, which is likely responsible for its acquisition. Sequence analysis indicates that ISCR5 is a chimera of ISCR3 and ISCR16.

Indexed as

Genes, BacterialBase Sequencebeta-LactamasesCodon, InitiatorDatabases, GeneticDatabases, ProteinDNA, BacterialDNA PrimersDNA Transposable ElementsHumansModels, GeneticMolecular Sequence DataOpen Reading FramesPseudomonas aeruginosaSequence Homology, Nucleic Acidbeta-LactamasesCodon, InitiatorDNA, BacterialDNA PrimersDNA Transposable Elements

Identifiers

PMID19064894
PMCPMC2650518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.