Evidence map›Paper›PMID 19064648›Full record

ArticleAmerican journal of epidemiology2009

Simply ask them about their balance--future fracture risk in a nationwide cohort study of twins.

Helene Wagner, Håkan Melhus, Rolf Gedeborg, Nancy L Pedersen, Karl Michaëlsson

Open access · bronzeAbstract readTwin Study
In one paragraph

Article in American journal of epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Distal radius fractures and risk of incident neurocognitive disorders in older adults: a retrospective cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Observational
  10. A Study Protocol for Applying User Participation and Co-Learning-Lessons Learned from the eBalance Project.International journal of environmental research and public health · 2017
    Article
  11. The Impact of Disease and Drugs on Hip Fracture Risk.Calcified tissue international · 2017
    Article
  12. Article
  13. Fracture predictive ability of physical performance tests and history of falls in elderly women: a 10-year prospective study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Article
  14. Osteoporosis: the emperor has no clothes.Journal of internal medicine · 2015
    Review
  15. Article
  16. One-leg standing time and hip-fracture prediction.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Article
  17. Persistent mucosal damage and risk of fracture in celiac disease.The Journal of clinical endocrinology and metabolism · 2014
    Article
  18. Article
  19. Predictors of the rate of BMD loss in older men: findings from the CHAMP study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Helene WagnerDepartment of Surgical Sciences, Section of Orthopaedics, University Hospital, Uppsala, Sweden.
Håkan Melhus
Rolf Gedeborg
Nancy L Pedersen
Karl Michaëlsson
Uppsala University Hospital · SE

Funding

DEMENTIA IN TWINSR01AG008724 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET · 1990 to 2002
$1.4M
NIA NIH HHS AG 08724NIA NIH HHS R01 AG008724
6 · The paper itself

Abstract

The principal causal components of an osteoporotic fracture are a fall and weakened bone strength. While bone quality measures have been frequently studied, the ability of simple measures of impaired balance to predict fracture risk has received less attention. Computer-assisted telephone interviews were conducted between 1998 and 2000 among 24,598 Swedish twins aged 55 years or older. Impaired balance at the time of interview was reported by 2,890 (12%) of the twins. Twin pairs who were discordant with regard to impaired balance were selected for analysis and followed for fractures through 2005. In a pairwise analysis, the odds ratio for hip fracture was 3.13 (95% confidence interval (CI): 1.62, 6.05) among twins with impaired balance as compared with their co-twins with normal balance. When previously recognized clinical risk factors for osteoporotic fracture were considered in the model, the odds ratio for hip fracture with impaired balance was 3.88 (95% CI: 1.40, 10.72). Approximately 40% of all hip fractures were attributable to impaired balance. The odds ratios for any fracture and any osteoporotic fracture for twins with impaired balance were 2.00 (95% CI: 1.29, 3.11) and 2.39 (95% CI: 1.49, 3.82), respectively. These results imply that self-reported impaired balance is a novel and readily assessed risk factor for future fractures in the elderly.

Indexed as

Postural BalanceTwinsAccidental FallsAgedAged, 80 and overConfidence IntervalsFemaleFrail ElderlyHip FracturesHumansMaleMiddle AgedOdds RatioOsteoporosisProspective StudiesRegistries

Identifiers

PMID19064648
PMCPMC2727259
OpenAlexW2130690351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.