ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2009
The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
155 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Response Flexibility: The Role of the Lateral Habenula.Frontiers in behavioral neuroscience · 2022Pooled it
- Circadian Influences on the Habenula and Their Potential Contribution to Neuropsychiatric Disorders.Frontiers in behavioral neuroscience · 2021Pooled it
- Ancestral organisation and asymmetric circuit architecture of the habenula revealed in a basal ray-finned fish.Brain structure & function · 2026Article
- Article
- Modulation of habenula axon terminals supports action-outcome associations in larval zebrafish.Nature communications · 2026Article
- Microsurgical Anatomy of the Posterior Commissure and Habenular Commissure in the Human Cadaveric Brain.Brain sciences · 2026Article
- The Habenula's role in major depressive disorder: recent insights from preclinical and human studies.Translational psychiatry · 2026Review
- Heparan sulfate endosulfatases, Sulf1 and Sulf2, are required for formation of the medial habenula-interpeduncular nucleus circuit.Frontiers in neuroanatomy · 2026Article
- Effects of Electrical Stimulation and Lidocaine Injection of Lateral Habenula Nucleus in the Addicted Rats with Morphine Self-administration.Journal of medical signals and sensors · 2026Article
- Deletion or enhancement of alpha-2 nAChRs (Chrna2) induces unique lifespan behavioral deficits.Neuropharmacology · 2026Article
- Heart Rate Variability Biofeedback Alleviates Subthreshold Depression by Reconstructing the Brain-Heart Axis via Habenular Network Functional Connectivity Modulation.CNS neuroscience & therapeutics · 2025Article
- Molecular and Functional Divergence of Zebrafish Sox Paralogs Controlling Endoderm Formation and Left-Right Patterning.Genome biology and evolution · 2025Article
- Shentong Zhuyu Decoction Alleviates Neuropathic Pain in Mice by Inhibiting the NMDAR-2B Receptor-Mediated CaMKII/CREB Signaling Pathway in GABAergic Neurons of the Interpeduncular Nucleus.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors.Nature communications · 2025Article
- 3D spatial transcriptomics reveals the molecular structure of input and output pathways in the mouse olfactory bulb.bioRxiv : the preprint server for biology · 2025Article
- Swimming through asymmetry: zebrafish as a model for brain and behavior lateralization.Frontiers in behavioral neuroscience · 2025Review
- Role of Neural Circuits in Cognitive Impairment.Neurochemical research · 2024Review
- Two-photon all-optical neurophysiology for the dissection of larval zebrafish brain functional and effective connectivity.Communications biology · 2024Article
- Hyperactive mTORC1 disrupts habenula function and light preference in zebrafish model of Tuberous sclerosis complex.iScience · 2024Article
- Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain.Science (New York, N.Y.) · 2024Article
95 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The dorsal diencephalon, or epithalamus, contains the bilaterally paired habenular nuclei and the pineal complex. The habenulae form part of the dorsal diencephalic conduction (DDC) system, a highly conserved pathway found in all vertebrates. In this review, we shall describe the neuroanatomy of the DDC, consider its physiology and behavioural involvement, and discuss examples of neural asymmetries within both habenular circuitry and the pineal complex. We will discuss studies in zebrafish, which have examined the organization and development of this circuit, uncovered how asymmetry is represented at the level of individual neurons and determined how such left-right differences arise during development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.