ArticleAmerican journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics2008
Inheritance of susceptibility to root resorption associated with orthodontic force in mice.
Article in American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 26 citations in OpenAlex.
- HK2-mediated Glycolysis Inhibits Mineralization of Cementoblasts Under Compression by Suppressing the Piezo1/Wnt Signaling.International journal of medical sciences · 2025Article
- LITTIP/Lgr6/HnRNPK complex regulates cementogenesis via Wnt signaling.International journal of oral science · 2023Article
- Standardized assessment of bone micromorphometry around teeth following orthodontic tooth movement : A µCT split-mouth study in mice.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2022Article
- External apical root resorption in orthodontic patients: molecular and genetic basis.Journal of family medicine and primary care · 2020Review
- Heredity, Genetics and Orthodontics - How Much Has This Research Really Helped?Seminars in orthodontics · 2017Article
- Pathways in external apical root resorption associated with orthodontia.Orthodontics & craniofacial research · 2009Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
introductionExternal apical root resorption (EARR) is an unwanted sequelae of orthodontic treatment. Genetic factors account for approximately 64% of the EARR variation in humans. Inbred mice offer a model to control the environmental factors and genetic heterogeneity that complicate human genetic studies. Genetically distinct inbred mice and their offspring (F1s) were analyzed to examine the mode of inheritance and the influence of parental sex on the susceptibility to root resorption associated with orthodontic force (RRAOF).
methodsRRAOF was determined histologically for male and female mice of the A/J, DBA/2J, and BALB/cJ strains, and the A/JxDBA/2J and A/JxBALB/cJ crosses (10 males and 10 females/reciprocal cross). RRAOF was induced by tipping the maxillary first molar mesially for 9 days.
resultsSex differences were observed only among the mice of the BALB/cJ strain. Two patterns of inheritance were observed; F1s from the A/JxBALB/cJ cross were resistant, suggesting that the A/J have dominant resistance alleles. On the other hand, F1s from the A/JxDBA/2J cross showed RRAOF intermediate between their parental mice, suggesting a polygenic trait.
conclusionsThese results provide evidence of a traceable and polygenetic component affecting RRAOF in mice.
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