ArticleAnalytical chemistry2009
Method of creating a nanopore-terminated probe for single-molecule enantiomer discrimination.
Article in Analytical chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 105 citations in OpenAlex.
- Hybrid Microtubule-Solid-State Nanopores for Single-Molecule Analysis.Electrophoresis · 2026Article
- Nanopipettes as a Potential Diagnostic Tool for Selective Nanopore Detection of Biomolecules.Biosensors · 2024Review
- Review
- Controllable Shrinking Fabrication of Solid-State Nanopores.Micromachines · 2022Review
- Nanopore Fabrication and Application as Biosensors in Neurodegenerative Diseases.Critical reviews in biomedical engineering · 2020Review
- Wireless nanopore electrodes for analysis of single entities.Nature protocols · 2019Article
- FIB-Milled Quartz Nanopores in a Sealed Nanopipette.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2019Article
- Making of a single solid-state nanopore on the wall of fused silica capillary.Royal Society open science · 2018Article
- Label-Free Detection of DNA Mutations by Nanopore Analysis.ACS applied materials & interfaces · 2018Article
- Discrimination of supramolecular chirality using a protein nanopore.Chemical science · 2017Article
- Conductivity-based detection techniques in nanofluidic devices.The Analyst · 2015Review
- Resistive-Pulse Measurements with Nanopipettes: Detection of Vascular Endothelial Growth Factor C (VEGF-C) Using Antibody-Decorated Nanoparticles.Analytical chemistry · 2015Article
- Article
- Nanopore detection of copper ions using a polyhistidine probe.Biosensors & bioelectronics · 2014Article
- Resistive-pulse measurements with nanopipettes: detection of Au nanoparticles and nanoparticle-bound anti-peanut IgY.Chemical science · 2013Article
- Mass transport through vertically aligned large diameter MWCNTs embedded in parylene.Nanotechnology · 2012Article
- Real-time sensing and discrimination of single chemicals using the channel of phi29 DNA packaging nanomotor.ACS nano · 2012Article
- Translocation of single-stranded DNA through the α-hemolysin protein nanopore in acidic solutions.Electrophoresis · 2011Article
- Robust properties of membrane-embedded connector channel of bacterial virus phi29 DNA packaging motor.Molecular bioSystems · 2010Article
- Functionalized nanopipettes: toward label-free, single cell biosensors.Bioanalytical reviews · 2010Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Nanopores are increasingly utilized as tools for single-molecule detection in biotechnology. Many nanopores are fabricated through procedures that require special materials, expensive facilities and experienced operators, which limit their usefulness on a wider scale. We have developed a simple method of fabricating a robust, low-noise nanopore by externally penetrating a nanocavity enclosed in the terminal of a capillary pipet. The nanocavity was shown to have a pore size on the scale of a single molecule, verified by translocation of molecules of known sizes, including double-stranded DNA (2 nm), gold nanoparticles (10 nm), and ring-shaped cyclodextrin (1.5 nm). The small pore size allows entrapment of a single cyclodextrin molecule. The glass nanopore with a trapped cyclodextrin proves useful in single-molecule discrimination of chiral enantiomers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.