ArticleClinics (Sao Paulo, Brazil)2008
The relationship between heart rate reserve and oxygen uptake reserve in heart failure patients on optimized and non-optimized beta-blocker therapy.
Article in Clinics (Sao Paulo, Brazil), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Rate adaptive pacing in people with chronic heart failure increases peak heart rate but not peak exercise capacity: a systematic review.Heart failure reviews · 2023Pooled it
- Measuring long-term physical activity in patients with heart failure and its relation to health-related outcomes.ESC heart failure · 2026Observational
- The importance of ventilatory thresholds to define aerobic exercise intensity in cardiac patients and healthy subjects.Scandinavian journal of medicine & science in sports · 2021Article
- Impact of β-Blockers on Heart Rate and Oxygen Uptake During Exercise and Recovery in Older Patients With Heart Failure With Preserved Ejection Fraction.Journal of cardiopulmonary rehabilitation and prevention · 2020Article
- Estimating metabolic equivalents for activities in daily life using acceleration and heart rate in wearable devices.Biomedical engineering online · 2018Article
- Alternatives to Aerobic Exercise Prescription in Patients with Chronic Heart Failure.Arquivos brasileiros de cardiologia · 2016Article
- Norepinephrine remains increased in the six-minute walking test after heart transplantation.Clinics (Sao Paulo, Brazil) · 2010Article
- Hydrotherapy in heart failure: a case report.Clinics (Sao Paulo, Brazil) · 2009Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between the percentage of oxygen consumption reserve and percentage of heart rate reserve in heart failure patients either on non-optimized or off beta-blocker therapy is known to be unreliable. The aim of this study was to evaluate the relationship between the percentage of oxygen consumption reserve and percentage of heart rate reserve in heart failure patients receiving optimized and non-optimized beta-blocker treatment during a treadmill cardiopulmonary exercise test.
methodsA total of 27 sedentary heart failure patients (86% male, 50+/-12 years) on optimized beta-blocker therapy with a left ventricle ejection fraction of 33+/-8% and 35 sedentary non-optimized heart failure patients (75% male, 47+/-10 years) with a left ventricle ejection fraction of 30+/-10% underwent the treadmill cardiopulmonary exercise test (Naughton protocol). Resting and peak effort values of both the percentage of oxygen consumption reserve and percentage of heart rate reserve were, by definition, 0 and 100, respectively.
resultsThe heart rate slope for the non-optimized group was derived from the points 0.949+/-0.088 (0 intercept) and 1.055+/-0.128 (1 intercept), p<0.0001. The heart rate slope for the optimized group was derived from the points 1.026+/-0.108 (0 intercept) and 1.012+/-0.108 (1 intercept), p=0.47. Regression linear plots for the heart rate slope for each patient in the non-optimized and optimized groups revealed a slope of 0.986 (almost perfect) for the optimized group, but the regression analysis for the non-optimized group was 0.030 (far from perfect, which occurs at 1).
conclusionThe relationship between the percentage of oxygen consumption reserve and percentage of heart rate reserve in patients on optimized beta-blocker therapy was reliable, but this relationship was unreliable in non-optimized heart failure patients.
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