Evidence map›Paper›PMID 19057730›Full record

SynthesisCanadian journal of surgery. Journal canadien de chirurgie2008

Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review.

Pasqualina L Santaguida, Gillian A Hawker, Pamela L Hudak, Richard Glazier, Nizar N Mahomed, Hans J Kreder, Peter C Coyte, James G Wright

Abstract readSystematic Review
PubMed Full text at PMC
In one paragraph

Synthesis in Canadian journal of surgery. Journal canadien de chirurgie, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 223 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
223citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

223 citing papers in PubMed, 15 syntheses or guidelines pooled it.

  1. Pooled it
  2. Distal Femoral Varus Osteotomy in Valgus Knee With Lateral Compartment Osteoarthritis: A Systematic Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Guideline
  15. Pooled it
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

163 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pasqualina L SantaguidaEvidence-based Practice Centre, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario.
Gillian A Hawker
Pamela L Hudak
Richard Glazier
Nizar N Mahomed
Hans J Kreder
Peter C Coyte
James G Wright

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotal joint arthroplasty is a highly efficacious and cost-effective procedure for moderate to severe arthritis in the hip and knee. Although patient characteristics are considered to be important determinants of who receives total joint arthroplasty, no systematic review has addressed how they affect the outcomes of total joint arthroplasty. This study addresses how patient characteristics influence the outcomes of hip and knee arthroplasty in patients with osteoarthritis.

methodsWe searched 4 bibliographic databases (MEDLINE 1980-2001, CINAHL 1982-2001, EMBASE 1980-2001, HealthStar 1998-1999) for studies involving more than 500 patients with osteoarthritis and 1 or more of the following outcomes after total joint arthroplasty: pain, physical function, postoperative complications (short-and long-term) and time to revision. Prognostic patient characteristics of interest included age, sex, race, body weight, socioeconomic status and work status.

resultsSixty-four of 14,276 studies were eligible for inclusion and had extractable data. Younger age (variably defined) and male sex increased the risk of revision 3-fold to 5-fold for hip and knee arthroplasty. The influence of weight on the risk of revision was contradictory. Mortality was greatest in the oldest age group and among men. Function for older patients was worse after hip arthroplasty (particularly in women). Function after knee arthroplasty was worse for obese patients.

conclusionAlthough further research is required, our findings suggest that, after total joint arthroplasty, younger age and male sex are associated with increased risk of revision, older age and male sex are associated with increased risk of mortality, older age is related to worse function (particularly among women), and age and sex do not influence the outcome of pain. Despite these findings, all subgroups derived benefit from total joint arthroplasty, suggesting that surgeons should not restrict access to these procedures based on patient characteristics. In addition, future research needs to provide standardized measures of outcomes.

Indexed as

AgedAged, 80 and overAge FactorsArthroplasty, Replacement, HipArthroplasty, Replacement, KneeFemaleHumansJoint DiseasesMaleMiddle AgedPrognosisReoperationSex FactorsTreatment Outcome

Identifiers

PMID19057730
PMCPMC2592576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.