ArticleEnvironmental health perspectives2008
Prospective analysis of traffic exposure as a risk factor for incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study.
Article in Environmental health perspectives, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Projecting non-communicable diseases attributable to air pollution in the climate change era: a systematic review.BMJ open · 2024Pooled it
- Built Environment, Selected Risk Factors and Major Cardiovascular Disease Outcomes: A Systematic Review.PloS one · 2016Pooled it
- Residential traffic exposure and childhood leukemia: a systematic review and meta-analysis.American journal of preventive medicine · 2014Pooled it
- Traffic-related air pollution and selected birth defects in the San Joaquin Valley of California.Birth defects research. Part A, Clinical and molecular teratology · 2013Trial
- Cardiovascular health among young adults: Do childhood neighborhoods matter?SSM - population health · 2026Article
- Social determinants of health across the lifecourse and chronic disease risk: available data and seminal findings from the Atherosclerosis Risk in Communities (ARIC) Study.American journal of epidemiology · 2026Review
- Rethinking 15-min walkable neighborhoods for healthy aging: evidence from cardiovascular health in Shanghai's older adults.Frontiers in public health · 2025Article
- Neighborhood attributes and cardiovascular disease risk in breast cancer survivors: The Pathways Study.Cancer · 2023Article
- Article
- Importance of Housing and Cardiovascular Health and Well-Being: A Scientific Statement From the American Heart Association.Circulation. Cardiovascular quality and outcomes · 2020Review
- Deciphering the stroke-built environment nexus in transitional cities: Conceptual framework, empirical evidence, and implications for proactive planning intervention.Cities (London, England) · 2019Article
- Prenatal exposure to air pollution, maternal diabetes and preterm birth.Environmental research · 2019Article
- Within-subject effects of environmental and social stressors on pre- and post-partum obesity-related biobehavioral responses in low-income Hispanic women: protocol of an intensive longitudinal study.BMC public health · 2019Article
- Green spaces and mortality due to cardiovascular diseases in the city of Rio de Janeiro.Revista de saude publica · 2018Article
- Exposure to air pollution and self-reported effects on Chinese students: A case study of 13 megacities.PloS one · 2018Article
- Costs of coronary heart disease and mortality associated with near-roadway air pollution.The Science of the total environment · 2017Article
- Traffic-related air pollution is associated with cardio-metabolic biomarkers in general residents.International archives of occupational and environmental health · 2016Article
- Near-Roadway Air Pollution and Coronary Heart Disease: Burden of Disease and Potential Impact of a Greenhouse Gas Reduction Strategy in Southern California.Environmental health perspectives · 2016Article
- Association between satellite-based estimates of long-term PM2.5 exposure and coronary artery disease.Environmental research · 2016Article
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundFor people living close to busy roads, traffic is a major source of air pollution. Few prospective data have been published on the effects of long-term exposure to traffic on the incidence of coronary heart disease (CHD).
objectivesIn this article, we examined the association between long-term traffic exposure and incidence of fatal and nonfatal CHD in a population-based prospective cohort study.
methodsWe studied 13,309 middle-age men and women in the Atherosclerosis Risk in Communities study, without previous CHD at enrollment, from 1987 to 1989 in four U.S. communities. Geographic information system-mapped traffic density and distance to major roads served as measures of traffic exposure. We examined the association between traffic exposure and incident CHD using proportional hazards regression models, with adjustment for background air pollution and a wide range of individual cardiovascular risk factors.
resultsOver an average of 13 years of follow-up, 976 subjects developed CHD. Relative to those in the lowest quartile of traffic density, the adjusted hazard ratio (HR) in the highest quartile was 1.32 [95% confidence interval (CI), 1.06-1.65; p-value for trend across quartiles = 0.042]. When we treated traffic density as a continuous variable, the adjusted HR per one unit increase of log-transformed density was 1.03 (95% CI, 1.01-1.05; p = 0.006). For residents living within 300 m of major roads compared with those living farther away, the adjusted HR was 1.12 (95% CI, 0.95-1.32; p = 0.189). We found little evidence of effect modification for sex, smoking status, obesity, low-density lipoprotein cholesterol level, hypertension, age, or education.
conclusionHigher long-term exposure to traffic is associated with incidence of CHD, independent of other risk factors. These prospective data support an effect of traffic-related air pollution on the development of CHD in middle-age persons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.